Table 2.
Baseline characteristics according to LA size
| All participants (N=34713) | AF without LA enlargement (N=468) | AF with LA enlargement (N=328) | P value* | |
|---|---|---|---|---|
| Age, years | 53 (49–59) | 58 (52–64) | 60 (54–65) | 0.003 |
| Height, m | 1.65 (1.60–1.68) | 1.65 (1.60–1.70) | 1.65 (1.63–1.70) | 0.04 |
| Body weight, kg | 68 (60–77) | 69 (61–82) | 75 (66–90) | <0.0001 |
| Body mass index, kg/m2 ‡ | 24.9 (22.5–28.3) | 25.6 (22.8–29.2) | 27.4 (24.2–32.1) | <0.0001 |
| Hypertension, % | <0.0001 | |||
| Yes | 8759 (25.2) | 163 (34.9) | 162 (50.6) | |
| No | 25947 (74.8) | 304 (65.1) | 166 (49.4) | |
| Diabetes, % | 0.01 | |||
| Yes | 845 (2.4) | 13 (2.8) | 21 (6.4) | |
| No | 33851 (97.6) | 455 (97.2) | 307 (93.6) | |
| Hypercholesterolemia, % | 0.17 | |||
| Yes | 10106 (29.1) | 152 (32.5) | 122 (37.2) | |
| No | 24593 (70.9) | 316 (67.5) | 206 (62.8) | |
| Smoking, % | 0.54 | |||
| Current/Past | 16783 (48.4) | 231 (49.5) | 169 (51.7) | |
| Never | 17904 (51.6) | 236 (50.5) | 158 (48.3) | |
| ≥2 alcoholic drinks / day, % | 1359 (3.9) | 19 (4.1) | 20 (6.1) | 0.19 |
| Physical activity, % | 0.64 | |||
| Rarely/Never | 13088 (37.7) | 209 (44.7) | 150 (45.9) | |
| < 1x/week | 6880 (19.8) | 90 (19.2) | 55 (16.8) | |
| 1-3x/week | 10960 (31.6) | 125 (26.7) | 84 (25.7) | |
| ≥ 4/week | 3770 (10.9) | 44 (9.4) | 38 (11.6) | |
| Race/ethnicity, % | 0.10 | |||
| White | 32736 (95.1) | 450 (97.0) | 320 (98.8) | |
| Other | 1678 (4.9) | 14 (3.0) | 4 (1.2) | |
| Paroxysmal AF | - | 346 (73.9) | 149 (45.4) | <0.0001 |
| Echocardiography >1 month after AF onset | - | 41 (8.8) | 52 (15.9) | 0.002 |
AF=Atrial fibrillation; LA=Left atrial. Data are medians (interquartile range) or counts (percentages). Number of observations across categories may not sum to the given numbers because of missing data.
*
P value comparing women with incident AF with versus without LA enlargement. Continuous and categorical variables were compared using Kruskal-Wallis tests and chi-square tests, respectively.