A. Starved HT-29 cells were treated with 1.5 μM cPAF or vehicle for 10, 30, and 240 min at 37°C. The levels of pAkt473, Akt, and β-actin then were determined in protein lysates, using immunoblot analyses.
B. Starved HCT-116 and LoVo cells were treated with 1.5 μM cPAF or vehicle for 30 min at 37°C. The levels of pAkt473, Akt, and β-actin then were determined using immunoblot analyses, as above.
C. Starved HT-29 cells were treated with cPAF or vehicle for 30 min at 37°C. The levels of pAkt308, pAkt473, Akt and β-actin then were determined as above.