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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Cancer Res. 2013 Jan 29;73(9):2806–2816. doi: 10.1158/0008-5472.CAN-12-2374

Table 1.

Deletion of Pla2g7 decreases polyp number in the Apc Min/+ model of intestinal polyposis

Apc Min/+ Apc Min/+/Pla2g7−/− p
n 17 21 -
Number of males (%) 7 (41%) 12 (57%) -
Number of females (%) 10 (59%) 9 (43%) -
Median age, days 98 98 -
Age range, days 84 – 100 78 – 102 -
Proximal intestinal polyps * 5.4 ± 2.6 3.0 ± 2.2 0.0010
Mid intestinal polyps * 26.1 ± 12.3 12.0 ± 7.6 5.2 × 10−5
Distal intestinal polyps * 42.0 ± 17.4 22.1 ± 16.0 0.0004
Colon polyps * 0.6 ± 1.7 0.3 ± 0.6 0.2458
Colon tumors** 1.6 ± 1.3 0.5 ± 0.9 0.0020
*

Data reported represent the average number of polyps per mouse ± S.D.

**

Data reported represent the average number of tumors per mouse ± S.D.