. 2013 Jan 1;3(1):e23181. doi: 10.4161/spmg.23181

Table 1. Possible roles of Wnt-β catenin signaling in the male reproductive system.

Tissue	Possible roles	Refs.
Testis	Fetal: - Differentiation of Mullerian duct, organization of testicular cords, development of primordial germ cells Postnatal: - Blood testis barrier (basal ES) and adherens junctions between Sertoli and germ cells (apical ES) - Germ cell differentiation - Proliferation of spermatogonia - Germ cell apoptosis - Sertoli cell proliferation, testicular tumors	⁴⁸^–⁵⁰ ⁵³ ⁵⁴ ⁴⁴^,⁵⁵ ⁵⁷^,⁵⁸ ³^,⁴^,⁵⁹
Epididymis	- Adherens juctions and formation of blood epididymal barrier	⁶²
Prostate	- Epithelial branching morphogenesis - Luminal epithelial cell differentiation - Proliferation and epithelial progenitor cells - Cancer	²²^,⁷⁵^,³⁸ ²²^,⁷⁶^,³⁸ ²²^,⁷⁶ ⁵^,²²^,⁷⁷^–⁸⁴