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Figure 5. ZO-1 localization is disorganized in carcinoma in situ, in the presence of normal connexin 43 reactivity. Confocal immunofluorescence of normal human testis (A) and carcinoma in situ (B) detecting ZO-1 (tight and associated junctions, red, asterisks) and connexin 43 (gap junctions, green, triangles). Inserts are negative controls. (Bar = 50 µm).
