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AFM images in tapping mode on air showing the effects induced on pEGFP-C1 plasmid DNA folding by incubation with (a) 2 μM argininocalixarene 3a; (b) 1 μM argininocalixarene 6; (c) 2 μM lysinocalixarene 3b in presence of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine) 4 μM; and (d) image of pEGFP-C1 plasmid DNA 0.5 nM alone. Each image represents a 2 × 2 μm scan.
