Table 1.
Hormonal levels, testicular volume and seminal features in secretory azo/oligozoospermic and control men
| n | FSHa (mIU/ml) | LHa (mIU/ml) | Testosteronea ng/ml | % of patients with testes <30 ccb | Sperm countc mill/mL | % of men with azoospermia | |
|---|---|---|---|---|---|---|---|
| Secretory azo/oligozoospermic group | 218 | ||||||
| Sertoli Cell Only Syndrome (SCOS) | 102 | 15.2 (5.4–44.5)e,g | 5.1 (1.5–14.5)e,g | 3.3 (1.6–6.1)e | 67e | 0.03 ± 0.16 (0–0.8) | 89e,l |
| Maturation Arrest (MA) | 38 | 7.7 (1.8–25.9)e,g | 3.4 (1.3–13.8)e,g | 3.3 (1.8–7.1) | 46e | 0.11 ± 0.47 (0–5) | 73e |
| Mixed Atrophy (MxA) | 20 | 14.4 (2.7–38.3)e,h | 4.8 (1.7–21.1)e,g | 3.0 (0.9–5.6) | 78e | 0.34 ± 1.17 (0–5) | 90e |
| Hypospermatogenesis (HS) | 16 | 5.2 (1.4–17.7)f,g | 4.2 (1.5–7.3)e,g | 3.9 (1.9–6.3) | 33h,i | 0.54 ± 1.31 (0–5) | 63 |
| Severe Atrophy (SA) | 10 | 30.4 (7.9–67)e | 13.4 (4.0–21.8)e | 2.8 (0.8–4.7)f | 89e | 0 | 100e |
| Without diagnosys by testicular biopsyd (WB) | 32 | 11.7 (3.4–53.3)e,g | 4.6 (1.8–13.6)e,g | 4.1 (2.0–6.7)g | 93e,j,k | 0.83 ± 1.36 (0–5.1) | 44m |
| Countrol groupn | 182 | 3.0 (2.0–4.3) | 2.4 (1.6–3.8) | 3.6 (2.9–4.5) | 7 | 55.8 ± 60.5 (0–218.6) | 32 |
| Total | 400 | ||||||
aMedian (2.5–97.5 percentiles)
bCombined testicular volume
cMillions of spermatozoa/mL, mean ± DS (range)
dElevated FSH and/or combined testicular volume <30 cc
eP < 0.01 vs. control group; fP < 0.05 vs. control group; gP < 0.01 vs. SA; hP < 0.05 vs. SA
iP < 0.05 vs. MxA; jP < 0.05 vs. SCOS; kP < 0.01 vs. DM; lP < 0.01 vs. SCOS; mP < 0.01 vs. MxA, SA
nAzo/oligozoospermic obstructive (n = 66), fertile (n = 17) and normozoospermic men (n = 99)
Hormonal normal ranges: FSH (1.0–7.0 mUI/ml), LH (1.0–8.0 mUI/ml), Testosterone (2.0–8.0 ngml)