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. 2013 Mar 15;126(6):1464–1476. doi: 10.1242/jcs.120915

Fig. 3.

Fig. 3.

Tspan18 knockdown inconsistently enhances neural crest migration. (A–F) Embryos unilaterally electroporated with ContMO (A,B) or TS18MO (C–F) were processed by whole mount in situ hybridization for Sox10 at 8 or 9 somites (A,C,D, dorsal view, anterior embryo half; A′,C′,D′, construct targeting; B,E,F, midbrain transverse sections at the level indicated). Neural crest migration is unaffected by ContMO (A,B, arrows). TS18MO-electroporated neural crest cells migrated normally in most embryos (C,E, arrows), but was enhanced in 28.1% of embryos (D,F, arrowheads). (G) Bar graph represents the frequency of embryos with enhanced or normal migration.