Table 4.
Functional and symptom scales in QLQ-BR23a
| |
Functional scales in BR 23b |
Symptom scale in BR 23c |
||||||
|---|---|---|---|---|---|---|---|---|
| Characteristic | Body Image | Sexual functioning | Sexual enjoyment | Future perspective | Systemic therapy side effect | Breast symptoms | Arm symptoms | Upset by hair loss |
| Age |
|
|
|
|
|
|
|
|
| ≤50 year |
72.53(31.24) |
29.25(29.88) |
48.91(34.02) |
55.55(39.69) |
20.07(18.66) |
16.35(19.75) |
39.09(31.74) |
51.41(43.47) |
| >50 years |
79.88(27.45) |
21.38(29.16) |
47.86(28.40) |
68.97(37.78) |
18.19(16.52) |
10.06(14.87) |
33.22(31.64) |
39.02(41.43) |
| P-value |
0.134 |
0.744 |
0.103 |
0.257 |
0.453 |
0.034 |
0.983 |
0.257 |
| Time since diagnosis |
|
|
|
|
|
|
|
|
| Early diagnosed |
65.47(37.33) |
18.09(27.52) |
55.55(35.76) |
44.76(44.23) |
25.85(19.77) |
20.95(22.17) |
43.80(32.44) |
70.83(34.15) |
| Transitional period |
75.67(30.32) |
23.65(27.71) |
44.44(27.89) |
63.22(39.06) |
17.83(17.28) |
11.11(14.45) |
32.18(29.57) |
41.49(42.23) |
| Long term survivors |
80.33(23.83) |
33.33(32.76) |
52.27(36.22) |
65.77(35.92) |
18.59(17.10) |
14.55(20.50) |
40.59(34.19) |
41.90(44.53) |
| P-value |
0.292 |
0.027 |
0.338 |
0.037 |
0.065 |
0.044 |
0.093 |
0.035 |
| Marital status |
|
|
|
|
|
|
|
|
| Single |
74.63(34.31) |
5.07(16.99) |
66.66(−) |
60.86(44.55) |
25.05(25.32) |
13.40(24.71) |
35.26(29.89) |
33.33(40.20) |
| Married |
73.88(29.97) |
37.47(29.33) |
48.83(32.03) |
61.63(38.46) |
16.96(14.81) |
14.30(17.74) |
38.22(31.81) |
43.28(43.03) |
| Divorced |
80.95(27.62) |
4.76(12.10) |
0.00(−) |
52.38(46.61) |
30.95(20.09) |
18.45(16.72) |
35.71(31.17) |
86.66(32.20) |
| Widowed |
81.25(27.59) |
0.00 (0.00) |
- |
63.33(38.34) |
20.95(20.51) |
9.58(15.04) |
31.11(33.30) |
43.33(38.65) |
| P-value |
0.446 |
0.000 |
0.288 |
0.877 |
0.060 |
0.046 |
0.484 |
0.020 |
| Educational level |
|
|
|
|
|
|
|
|
| Illiterate |
82.32(27.79) |
24.71(31.87) |
52.56(30.07) |
75.00(33.96) |
16.06(14.95) |
9.72(15.65) |
32.03(31.36) |
28.07(40.46) |
| Primary |
78.88(25.49) |
11.11(22.46) |
33.33(30.86) |
57.77(40.05) |
21.11(17.58) |
13.61(20.81) |
43.70(34.39) |
71.42(40.49) |
| Intermediate |
71.01(33.32) |
28.98(32.26) |
52.77(30.01) |
63.76(44.84) |
17.59(20.47) |
16.30(16.94) |
35.26(34.26) |
75.00(38.83) |
| High school/diploma |
75.30(30.46) |
26.95(27.20) |
44.20(34.46) |
55.14(39.84) |
20.92(18.87) |
15.12(18.49) |
36.35(30.73) |
40.47(41.99) |
| College |
67.26(31.20) |
34.52(31.96) |
55.55(30.56) |
54.76(38.83) |
20.18(17.90) |
15.07(18.88) |
39.15(31.44) |
55.07(42.17) |
| P -value |
0.029 |
0.015 |
0.417 |
0.026 |
0.432 |
0.490 |
0.067 |
0.021 |
| Employment |
|
|
|
|
|
|
|
|
| Yes |
76.19(28.31) |
29.25(30.90) |
53.33(34.69) |
50.66(38.82) |
20.47(19.76) |
16.66(20.68) |
38.00(30.12) |
51.38(40.50) |
| No |
75.57(30.84) |
24.94(29.14) |
47.29(31.69) |
63.69(38.93) |
18.42(17.08) |
13.47(18.10) |
35.31(32.35) |
42.30(43.34) |
| Retired |
75.20(28.77) |
25.41(31.12) |
47.05(31.31) |
65.83(40.28) |
20.83(17.80) |
10.62(13.73) |
39.44(32.11) |
50.72(45.91) |
| P-value |
0.885 |
0.697 |
0.756 |
0.070 |
0.683 |
0.425 |
0.610 |
0.558 |
| Monthly income |
|
|
|
|
|
|
|
|
| <500 |
75.38(30.40) |
17.30(25.95) |
42.85(30.42) |
60.60(40.52) |
21.51(17.70) |
13.63(18.34) |
35.35(30.44) |
47.27(42.88) |
| 500–999 |
75.00(29.37) |
35.38(31.82) |
50.00(35.30) |
61.40(40.72) |
17.62(20.91) |
14.91(17.23) |
37.42(33.89) |
43.05(43.38) |
| >1000 |
78.62(27.97) |
78.62(30.19) |
55.95(30.16) |
63.76(35.01) |
15.21(12.32) |
10.86(16.18) |
37.68 (32.32) |
48.33(45.20) |
| P-value |
0.780 |
0.000 |
0.231 |
0.965 |
0.035 |
0.354 |
0.901 |
0.906 |
| Menopausal status |
|
|
|
|
|
|
|
|
| Premenopause |
71.43(31.97) |
30.00(29.93) |
48.48(34.68) |
56.36(39.29) |
19.56(17.73) |
17.27(20.05) |
40.30(31.92) |
48.97(43.08) |
| Perimenopause |
77.31(28.28) |
26.85(29.08) |
49.01(26.66) |
56.48(41.26) |
20.50(20.22) |
15.74(19.08) |
34.87(32.00) |
54.76(46.42) |
| Postmenopause |
80.20(27.22) |
20.45(29.33) |
48.48(30.15) |
69.25 (37.80) |
18.408(16.88) |
8.42(13.42) |
32.71(31.31) |
39.81(42.02) |
| P-value |
0.091 |
0.049 |
0.985 |
0.047 |
0.876 |
0.001 |
0.169 |
0.473 |
| Pathological staging |
|
|
|
|
|
|
|
|
| Stage 0 and I |
76.28(28.26) |
22.64(26.34) |
43.75(33.81) |
60.68(41.09) |
19.65(13.69) |
17.09(18.72) |
42.16(32.16) |
56.25(48.25) |
| Stage II |
78.67(29.57) |
25.42(28.42) |
47.31(33.08) |
61.58(40.02) |
20.33(19.24) |
14.40(20.63) |
36.34(31.21) |
33.33(36.00) |
| Stage III and IV |
61.51(36.17) |
20.09(25.87) |
48.88(27.79) |
52.94(45.03) |
24.36(21.51) |
15.93(19.82) |
36.92(34.46) |
50.00(40.82) |
| P-value |
0.052 |
0.761 |
0.884 |
0.609 |
0.691 |
0.560 |
0.363 |
0.225 |
| Metastases |
|
|
|
|
|
|
|
|
| Yes |
71.56(35.36) |
14.70(24.21) |
33.33(36.51) |
47.05(39.19) |
36.13(29.26) |
28.43(25.52) |
54.24(35.54) |
43.33(44.58) |
| No |
75.96(29.46) |
26.80(30.03) |
49.39(31.84) |
62.40(39.26) |
17.95(15.91) |
12.51(16.90) |
35.21(31.12) |
46.81(43.14) |
| P-value |
0.585 |
0.117 |
0.299 |
0.131 |
0.013 |
0.008 |
0.033 |
0.831 |
| Mastectomy |
|
|
|
|
|
|
|
|
| Yes |
70.01(33.22) |
26.35(29.13) |
47.77(32.10) |
62.14(40.63) |
19.69(19.06) |
14.33(19.21) |
37.75(31.66) |
46.80(43.21) |
| No |
81.26(24.97) |
25.49(30.52) |
49.40(32.40) |
60.45(38.22) |
18.84(16.41) |
12.99(16.89) |
35.40(31.95) |
46.15(43.36) |
| P-value |
0.022 |
0.665 |
0.768 |
0.684 |
0.964 |
0.827 |
0.499 |
0.965 |
| Lumpectomy |
|
|
|
|
|
|
|
|
| Yes |
80.76(24.91) |
24.58(30.47) |
48.80(33.61) |
60.60(38.49) |
18.80(16.26) |
13.42(17.98) |
35.44(31.76) |
45.28(43.40) |
| No |
70.24(33.58) |
27.33(29.09) |
48.33(30.94) |
60.02(40.43) |
19.75(19.26) |
13.98(18.22) |
37.77(31.86) |
47.82(43.12) |
| P-value |
0.059 |
0.322 |
0.933 |
0.736 |
0.931 |
0.846 |
0.529 |
0.788 |
| Lymph node dissection |
|
|
|
|
|
|
|
|
| Yes |
74.53(30.39) |
25.75(29.59) |
47.81(33.38) |
59.50(39.52) |
19.59(17.60) |
13.12(17.15) |
37.22(31.87) |
48.23(43.18) |
| No |
81.42(26.66) |
25.71(30.87) |
52.08(24.24) |
70.47(37.72) |
17.50(19.07) |
15.71(22.11) |
32.06(31.28) |
38.46(42.70) |
| P-value |
0.249 |
0.884 |
0.754 |
0.115 |
0.406 |
0.728 |
0.348 |
0.434 |
| Chemotherapy |
|
|
|
|
|
|
|
|
| Yes |
73.89(30.73) |
27.03(29.70) |
48.14(33.40) |
60.17(39.97) |
20.10(18.26) |
14.29(18.49) |
37.95(31.22) |
46.89(42.58) |
| No |
82.78(25.05) |
21.37(29.95) |
50.98(23.91) |
65.94(36.84) |
15.76(15.15) |
11.05(16.10) |
30.91(33.69) |
43.58(47.88) |
| P-value |
0.071 |
0.161 |
0.781 |
0.387 |
0.144 |
0.213 |
0.097 |
0.806 |
| Radiotherapy |
|
|
|
|
|
|
|
|
| Yes |
76.56(29.28) |
26.14(30.12) |
50.34(31.83) |
61.11(39.27) |
18.37(16.86) |
13.25(17.79) |
36.64(31.58) |
43.20(42.30) |
| No |
70.72(32.78) |
24.77(28.22) |
38.88(32.83) |
62.28(40.39) |
24.06(21.58) |
15.78(19.54) |
36.25(33.15) |
61.11(44.64) |
| P-value | 0.335 | 0.970 | 0.193 | 0.837 | 0.220 | 0.389 | 0.869 | 0.117 |
aP-value based on Kruskal Wallis or Mann Whitney tests.
bFor functional scales, higher scores indicate better functioning.
cFor symptom scales, higher scores indicate worse functioning.