Table 5.
Final linear regression model with parameter estimates for QLQ functional scales
| |
Global QoL score |
Physical functioning |
Role functioning |
Emotional functioning |
Cognitive functioning |
Social functioning |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Variable | Standardized Coefficients Beta | Significance | Standardized Coefficients Beta | Significance | Standardized Coefficients Beta | Significance | Standardized Coefficients Beta | Significance | Standardized Coefficients Beta | Significance | Standardized Coefficients Beta | Significance |
| Constant |
63.298 |
<0.001 |
36.082 |
0.024 |
56 |
0.032 |
77.93 |
0.001 |
71.909 |
0.001 |
41.898 |
0.047 |
|
Age > 50 |
−0.007 |
0.956 |
0.187 |
0.103 |
0.022 |
0.848 |
2.757 |
0.007 |
0.135 |
0.285 |
0 |
0.999 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Married |
0.116 |
0.231 |
0.129 |
0.168 |
0.076 |
0.434 |
0.837 |
0.404 |
0.11 |
0.288 |
0.35 |
<0.001 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Education |
−0.024 |
0.844 |
0.192 |
0.103 |
−0.021 |
0.861 |
−0.25 |
0.803 |
−0.112 |
0.384 |
−0.137 |
0.244 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Employment |
−0.018 |
0.853 |
−0.109 |
0.252 |
−0.078 |
0.429 |
−0.863 |
0.39 |
0.036 |
0.732 |
−0.054 |
0.571 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
High Income |
0.109 |
0.29 |
0.086 |
0.391 |
0.171 |
0.098 |
1.612 |
0.11 |
0.101 |
0.361 |
0.25 |
0.014 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Menopause |
−0.259 |
0.031 |
−0.128 |
0.269 |
0.068 |
0.565 |
−0.621 |
0.536 |
−0.01 |
0.934 |
0.034 |
0.769 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Advanced stage |
−0.275 |
0.005 |
−0.061 |
0.516 |
−0.189 |
0.051 |
−0.54 |
0.59 |
−0.106 |
0.304 |
−0.156 |
0.101 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Late survivors |
−0.105 |
0.263 |
−0.021 |
0.819 |
0.071 |
0.447 |
0.861 |
0.391 |
−0.067 |
0.506 |
−0.015 |
0.873 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Comorbidities |
−0.027 |
0.783 |
−0.046 |
0.63 |
0.054 |
0.58 |
−2.171 |
0.032 |
0.037 |
0.725 |
−0.088 |
0.363 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Metastases |
−0.086 |
0.385 |
−0.297 |
0.002 |
−0.303 |
0.003 |
−1.691 |
0.094 |
−0.174 |
0.1 |
−0.103 |
0.285 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Lumpectomy |
0.321 |
0.205 |
0.45 |
0.068 |
0.15 |
0.551 |
0.746 |
0.457 |
0.072 |
0.789 |
0.265 |
0.282 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Mastectomy |
0.319 |
0.203 |
0.417 |
0.087 |
0.109 |
0.659 |
0.938 |
0.35 |
0.128 |
0.632 |
0.166 |
0.495 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Lymph node dissection |
−0.068 |
0.461 |
0.052 |
0.559 |
−0.01 |
0.917 |
−1.763 |
0.081 |
−0.013 |
0.892 |
0.031 |
0.731 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Chemotherapy |
−0.033 |
0.743 |
−0.07 |
0.466 |
−0.061 |
0.535 |
−2.646 |
0.009 |
−0.095 |
0.371 |
−0.043 |
0.654 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Radiotherapy |
−0.085 |
0.376 |
0.159 |
0.089 |
0.061 |
0.524 |
0.139 |
0.89 |
−0.046 |
0.65 |
0.083 |
0.377 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Hormonal therapy |
0.036 |
0.688 |
−0.063 |
0.464 |
−0.178 |
0.047 |
−0.76 |
0.449 |
0.04 |
0.677 |
0.008 |
0.931 |
| No = 0 |
|
|
|
|
|
|
|
|
|
|
|
|
| Yes = 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
R squared |
0.24 |
0.28 |
0.25 |
0.25 |
0.132 |
0.281 |
||||||
| P-value | 0.015 | 0.002 | 0.009 | 0.01 | 0.455 | 0.002 | ||||||