Table 1.
Comparison of liver amino acid levels between the control and ALF groups
| No. | Retention Time | Amino Acids | Control Group | ALF Group | Ratioc | P |
|---|---|---|---|---|---|---|
| 1 |
6.98 |
alanine |
197.63 ± 25.91 |
162.54 ± 23.76 |
0.82 |
0.0889 |
| 2 |
9.87 |
valine |
81.52 ± 9.32 |
79.34 ± 13.53 |
0.97 |
0.8230 |
| 3 |
11.78 |
isoleucine |
41.67 ± 8.16 |
43.00 ± 5.56 |
1.03 |
0.8026 |
| 4 |
11.86 |
5-oxy-proline |
44.91 ± 11.28 |
50.17 ± 6.79 |
1.12 |
0.5499 |
| 5 |
12.10 |
glycine |
157.18 ± 18.62 |
120.83 ± 11.80 |
0.77 |
0.0208 |
| 6 |
13.53 |
serine |
98.42 ± 7.32 |
100.49 ± 9.06 |
1.02 |
0.7926 |
| 7 |
14.15 |
threonine |
88.84 ± 10.42 |
77.97 ± 7.22 |
0.88 |
0.1624 |
| 8 |
15.20 |
B-alanine |
38.87 ± 9.79 |
19.36 ± 1.63 |
0.50 |
0.0182 |
| 9 |
17.43 |
proline |
99.95 ± 17.81 |
74.37 ± 7.51 |
0.74 |
0.0472 |
| 10 |
17.53 |
aspartate |
54.20 ± 11.68 |
50.40 ± 4.85 |
0.93 |
0.6024 |
| 11 |
19.90 |
glutamate |
98.41 ± 15.86 |
77.18 ± 5.01 |
0.78 |
0.0491 |
| 12 |
20.98 |
asparagine |
2.06 ± 0.81 |
2.60 ± 0.78 |
1.26 |
0.5246 |
| 13 |
24.18 |
ornithine |
41.78 ± 10.86 |
67.31 ± 14.79 |
1.61 |
0.1087 |
| 14 |
25.57 |
tyrosine |
67.81 ± 9.84 |
32.34 ± 9.02 |
0.48 |
0.0008 |
| 15 |
26.37 |
lysine |
10.61 ± 1.61 |
64.29 ± 12.27 |
6.06 |
0.0008 |
| |
|
TAAa |
1123.87 ± 115.19 |
1022.21 ± 113.20 |
0.91 |
0.2207 |
| Gluconeogenic amino acidsb | 1003.66 ± 118.93 | 858.26 ± 85.36 | 0.86 | 0.0656 |
a Total amino acids. bGluconeogenic amino acids include aspartate, serine, glycine, threonine, alanine, proline, lysine, tyrosine, valine, and isoleucine. cMeans ratio of metabolite levels between ALF and control groups.