Table 2.
Significantly associated GO terms to only cancer-generic or tissue-centric contextual gene sets
|
GO terms relevant only to cancer-generic |
GO terms relevant only to tissue-centric |
||
|---|---|---|---|
| contextual gene sets | contextual gene sets | ||
|
GO term |
Frequency |
GO term |
Frequency |
| GO:0007166: cell surface receptor signal transduction |
11 |
GO:0006163: purine nucleotide metabolism |
2 |
| GO:0007049: cell cycle |
9 |
GO:0006164: purine nucleotide biosynthesis |
2 |
| GO:0006396: RNA processing |
7 |
GO:0006629: lipid metabolism |
2 |
| GO:0008283: cell proliferation |
7 |
GO:0009150: purine ribonucleotide metabolism |
2 |
| GO:0016070: RNA metabolism |
7 |
GO:0009152: purine ribonucleotide biosynthesis |
2 |
| GO:0043207: response to external biotic stimulus |
7 |
GO:0009259: ribonucleotide metabolism |
2 |
| GO:0000375: RNA splicing, via transesterification reactions |
6 |
GO:0009260: ribonucleotide biosynthesis |
2 |
| GO:0000377: RNA splicing, via transesterification reactions |
6 |
GO:0044255: cellular lipid metabolism |
2 |
| GO:0000398: nuclear mRNA splicing, via spliceosome |
6 |
GO:0046148: pigment biosynthesis |
2 |
| GO:0006397: mRNA processing |
6 |
GO:0000904: cellular morphogenesis |
1 |
| GO:0006959: humoral immune response |
6 |
GO:0006099: tricarboxylic acid cycle |
1 |
| GO:0008380: RNA splicing |
6 |
GO:0006119: oxidative phosphorylation |
1 |
| GO:0009613: response to pest, pathogen or parasite |
6 |
GO:0006144: purine base metabolism |
1 |
| GO:0016071: mRNA metabolism |
6 |
GO:0006188 : IMP biosynthesis |
1 |
| GO:0030333: antigen processing |
6 |
GO:0006189: ’de novo’ IMP biosynthesis |
1 |
| GO:0000067: DNA replication and chromosome cycle |
5 |
GO:0006510: ATP-dependent proteolysis |
1 |
| GO:0000075: cell cycle checkpoint |
5 |
GO:0006554: lysine catabolism |
1 |
| GO:0006950: response to stress |
5 |
GO:0006570: tyrosine metabolism |
1 |
| GO:0016064: humoral defense mechanism |
5 |
GO:0006582: melanin metabolism |
1 |
| GO:0000279: M phase | 4 | GO:0006583: melanin biosynthesis from tyrosine | 1 |
The frequency indicates the number of contextual gene sets associated with the corresponding GO term. Only 20 most frequent terms are shown for each case.