Table 2.

Description of excluded studies

	Citation	Key findings	Reason for exclusion
1	³⁸Ismail K, Winkley K, Stahl D, Chalder T, Edmonds M. A cohort study of people with diabetes and their first foot ulcer: the role of depression on mortality. Diabetes Care. 2007; 30(6): 1473-1479.	Minor and major depressive disorders were associated with an approximately threefold hazard risk for mortality compared with no depression (HR 3.23 [95% CI 1.39–7.51] and HR 2.73 [1.38–5.40], respectively).	Special population only: patients with first foot ulcer
2	³⁹Bot M, Pouwer F, Zuidersma M, van Melle JP, de Jonge P. Association of Coexisting Diabetes and Depression With Mortality After Myocardial Infarction. Diabetes Care. March 1, 2012 2012;35(3):503-509.³⁹	Hazard ratios for all-cause mortality were 1.38 (95% CI 1.00–1.90) for patients with diabetes only, and 2.90 (2.07–4.07) for patients with both diabetes and depression.	Special population only: Only patients Post-MI
3	⁴⁰Katon WJ, Rutter C, Simon G, et al. The Association of Comorbid Depression With Mortality in Patients With Type 2 Diabetes. Diabetes Care. November 2005 2005; 28(11): 2668-2672.	Minor depression was associated with a 1.67-fold increase in mortality (P = 0.003), and major depression was associated with a 2.30-fold increase (P < 0.0001).	Same patient population as used with Lin et al (2009), but only three-year follow-up
4	⁴¹Egede LE, Nietert PJ, Zheng D. Depression and all-cause and coronary heart disease mortality among adults with and without diabetes. Diabetes Care. Jun 2005;28(6):1339-1345.	Compared with the reference group, HRs for all-cause mortality were diabetes present, no depression 1.88 (1.55-2.27); and diabetes present, depression present, 2.50 (2.04-3.08).	Same data set as paper of Zhang et al (2005)
5	Lee TA, Shields AE, Vogeli C, et al. Mortality rate in veterans with multiple chronic conditions. J Gen Intern Med. Dec 2007;22 Suppl 3:403-407.	Veterans with depression and DM experienced lower five-year age adjusted mortality rate than those with diabetes only (OR: 6.50, 95% CI: 5.12, 7.88 vs. OR: 7.07, 95%CI: 6.75, 7.39).	Outcomes reported ORs, not HRs
6	⁴³Rosenthal MJ, Fajardo M, Gilmore S, Morley JE, Naliboff BD. Hospitalization and Mortality of Diabetes in Older Adults: A 3-year prospective study. Diabetes Care. February 1, 1998 1998;21(2):231- 235.	Compared to older adults with DM only, those with depression and DM experienced 1.32-fold increased mortality in 5-year follow-up period (OR: 1.32, 95% CI: 1.02, 1.70)	Outcomes reported as ORs, not HRs
7	⁴⁴Black SA, Markides KS. Depressive symptoms and mortality in older Mexican Americans. Ann Epidemiol. Jan 1999;9(1):45-52.	The odds of having died among diabetics with high levels of depressive symptoms (OR: 4.03, 95% CI: 2.67, 6.11) were three times that of diabetics without high levels of depressive symptoms (OR: 1.36, 95% CI: 0.89, 2.06).	Same data set as paper of Black et al (2003)
8	⁴⁵Prisciandaro JJ, Gebregziabher M, Grubaugh AL, Gilbert GE, Echols C, Egede LE. Impact of psychiatric comorbidity on mortality in veterans with type 2 diabetes. Diabetes Technol Ther. Jan 2011; 13(1): 73-78.	Only externalizing disorders were significantly associated with mortality: hazard ratio = 1.22 (95% confidence interval = 1.02-1.47).	Depression was not clearly defined. The authors categorized psychiatric disorder into two groups: internalizing and externalizing disorders and aggregated data about individuals with depression with other internalizing disorders (e.g. anxiety)
9	⁴⁶Reynolds SL, Haley WE, Kozlenko N. The Impact of Depressive Symptoms and Chronic Diseases on Active Life Expectancy in Older Americans. American Journal of Geriatric Psych. 2008; 16(5): 425-432 410.1097/JGP.1090b1013e31816ff31832e.	Depressive symptoms reduced active live expectancy by 6.5 years for young-old men (age 70), 3.2 years for old-old men (age 85), 4.2 years for young-old women, and 2.2 years for old-old women.	Outcome was life expectancy not mortality
10	⁴⁷Gallo JJ, Bogner HR, Morales KH, Post EP, Ten Have T, Bruce ML. Depression, cardiovascular disease, diabetes, and two-year mortality among older, primary-care patients. The American journal of geriatric psychiatry: official journal of the American Association for Geriatric Psychiatry. 2005; 13(9): 748-755.	Persons with depression at baseline were more likely to die at the end of the 2-year follow-up interval than were persons without depression (relative odds 1.81, 95% confidence interval [1.07, 3.05]; Wald χ2 = 4.96, df = 1, p = 0.03)	Data on individuals with MI and Diabetes were aggregated. Thus, unable to compare mortality among those with Depression and DM and those with DM only. The outcome was not reported as Hazard Ratio.
11	Bogner HR, Morales KH, Post EP, Bruce ML. Diabetes, depression, and death: a randomized controlled trial of a depression treatment program for older adults based in primary care (PROSPECT). Diabetes Care. 2007;30(12):3005-3010.	Depressed patients with diabetes in the intervention group were less likely to have died during the 5-year follow-up interval than depressed diabetic patients in usual care (adjusted HR 0.49, 95% CI 0.24-0.98)	Compares mortality rate between individuals who received depression treatment and those who were in comparison group. There was no way to compare the mortality among those with diabetes only and diabetes and depression.
12	⁴⁹Landman GWD, van Hateren KJJ, Kleefstra N, Groenier KH, Gans10 ROB, Bilo HJG. Health-Related Quality of Life and Mortality in a General and Elderly Population of Patients With Type 2 Diabetes (ZODIAC-18). Diabetes Care. November 1, 2010 2010; 33(11): 2378- 2382.	A 10-point-higher score on the Mental Component Score (MCS) decreased the risk for total mortality by 10%.	No clear depression cut-off point.
13	⁵⁰Milano A, Singer R. Mortality in co-morbidity (II)--excess death rates derived from a follow-up study on 10,025 subjects divided into 4 groups with or without depression and diabetes mellitus. J Insur Med. 2007;39(3):160-166.		Appear to be using Egede’s table for basis of their findings. No original data.