Table 3.
RESULTS FROM META-ANALYSIS AND META-REGRESSION
| Within group | Between Group | |||||||
|---|---|---|---|---|---|---|---|---|
| N of studies |
Pooled HRs |
95% CI | Cochran Q | p-value | I2 (%) | Cochran Q | p-value | |
| Meta-Analysis | ||||||||
| Random effects | 10 | 1.50 | 1.35, 1.66 | |||||
| Fixed effects | 10 | 1.48 | 1.36, 1.60 | |||||
| Meta-Regression | ||||||||
| Study site | 2.41 | 0.12 | ||||||
| U.S. | 7 | 1.50 | 1.39, 1.62 | 6.88 | 0.33 | 13 | ||
| Non-U.S. | 3 | 1.36 | 1.39, 1.62 | 0.51 | 0.78 | 0 | ||
| Study populations | 0.08 | 0.78 | ||||||
| Community-based | 6 | 1.46 | 1.27, 1.68 | 2.53 | 0.47 | 0 | ||
| Hospitals or Clinics | 4 | 1.66 | 1.38, 1.63 | 10.55 | 0.10 | 43 | ||
| Populations | 0.24 | 0.63 | ||||||
| Mixed-age | 7 | 1.47 | 1.33, 1.62 | 8.73 | 0.27 | 20 | ||
| Older adults | 3 | 1.56 | 1.24, 1.96 | 4.80 | 0.09 | 58 | ||
| Gender | 0.12 | 0.73 | ||||||
| Majority female | 7 | 1.47 | 1.34, 1.61 | 9.54 | 0.22 | 27 | ||
| Majority male | 3 | 1.55 | 1.15, 2.09 | 3.53 | 0.17 | 43 | ||
| Quality Scores | 0.28 | 0.60 | ||||||
| Less than or equal to 13.5 | 5 | 1.48 | 1.32, 1.64 | 4.97 | 0 .29 | 19.5 | ||
| Greater than >13.5 | 5 | 1.42 | 1.26, 1.58 | 6.07 | 0.30 | 17.7 | ||
| Mean follow-up years | 0.00 | 0.97 | ||||||
| Shorter than or equal to 6.5 years | 5 | 1.45 | 1.29, 1.62 | 2.43 | 0.66 | 0.0 | ||
| Longer than 6.5 years | 5 | 1.45 | 1.29, 1.60 | 8.89 | 0.11 | 43.7 | ||
| Number of observations | 0.18 | 0.67 | ||||||
| Less than or equal to 5000 | 7 | 1.42 | 1.26, 1.59 | 9.00 | 0.25 | 22.2 | ||
| Great than 5000 | 3 | 1.47 | 1.32, 1.62 | 2.13 | 0.34 | 6.2 | ||