Table 1.
Growth factor signaling pathways significantly differentially expressed between the Banff grades of CAN/IFTA
| Normals vs. CAN (Banff 1,2 &3) | p-value |
|---|---|
| HGF Signaling$ |
0.0001 |
| VEGF Signaling* |
0.0016 |
| EGF Signaling$ |
0.0017 |
| IGF-1 Signaling* |
0.0022 |
| TGF-β Signaling |
0.0056 |
| PDGF Signaling* |
0.0112 |
|
CAN Banff 0 vs. Banff 1 |
p-value |
| HGF Signaling$ |
0.0011 |
| FGF Signaling* |
0.0049 |
| PDGF Signaling* |
0.0105 |
| VEGF Signaling* |
0.0158 |
| EGF Signaling$ |
0.0178 |
|
CAN Banff 0 vs. Banff 2&3 |
p-value |
| EGF Signaling$ |
0.0145 |
| FGF Signaling* |
0.0257 |
| HGF Signaling$ |
0.0347 |
| IGF-1 Signaling* |
0.0447 |
|
CAN Banff 1 vs. Banff 2&3 |
p-value |
| IGF-1 Signaling* | 0.0447 |
*Significant in two comparisons.
$Significant in three or more comparisons.