Table 1.
Demographic and clinical characteristics
| Pt. No. | Age (yrs) | Gender | Ethnicity | Hypertension | Diabetes | Time From Chest Pain to PCI (min) |
Time From Chest Pain to Drug (min) |
Thrombolysis (Before PCI) |
CAD (culprit) |
CAD (other) |
TIMI Flow (Initial) |
TIMI Flow (Final) |
Coronary Stenting |
Infarct Size (%) |
Adverse Clinical Events | LVESVi (Admission) |
LVESVi (Follow-Up) |
Change in LVESVi (ml/m2) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Placebo | ||||||||||||||||||
| 1 | 60 | M | W | Y | N | 75 | 289 | N | RCA | N | 1 | 3 | Y | 5.0 | Acute coronary syndrome; Femoral artery pseudoaneurysm | 12.0 | 23.5 | + 11.5 |
| 3 | 28 | M | W | N | N | 664 | 1020 | Y | RCA | N | 2 | 3 | Y | 14.3 | None | 21.0 | 23.0 | +2.0 |
| 5 | 65 | M | B | Y | Y | 264 | 515 | Y | LAD | RCA | 0 | 3 | Y | 25.8 | Heart failure | 29.0 | 28.5 | –0.5 |
| 6 | 53 | M | W | N | N | 115 | 480 | N | RCA | LCX | 1 | 3 | Y | 7.1 | Unstable angina | 41.5 | 42.5 | +1.0 |
| 8 | 45 | M | B | Y | N | 139 | 390 | N | LCX | RCA | 0 | 3 | Y | 19.4 | Heart failure, atypical chest pain | 41.5 | 61.5 | +20.0 |
| Anakinra | ||||||||||||||||||
| 2 | 59 | M | W | Y | Y | 64 | 453 | N | LCX | LAD RCA | 0 | 3 | Y | 12.1 | None | 42.5 | 34.5 | –8.0 |
| 7 | 35 | F | W | Y | Y | 415 | 732 | N | LCX | N | 1 | 3 | N | 27.0 | None | 48.5 | 47.0 | –1.5 |
| 9 | 59 | M | W | Y | N | 192 | 470 | N | RCA | LAD | 1 | 3 | Y | 13.7 | None | 24.5 | 21.5 | –3.0 |
| 10 | 40 | M | W | Y | N | 267 | 472 | Y | RCA | N | 3 | 3 | Y | 25.8 | Injection site pain | 52.5 | 48.0 | –4.5 |
| 11 | 34 | F | W | Y | N | 140 | 583 | N | LAD | LCX | 0 | 3 | Y | 15.4 | Acute coronary syndrome, injection site pain | 31.0 | 29.5 | –1.5 |
B = black; W = white; CAD = coronary artery disease; F = female; LAD = left anterior descending (artery); LCX = left circumflex (artery); M = male; N = no; PCI = percutaneous coronary intervention; RCA = right coronary artery; TIMI = Thrombolysis In Myocardial Infarction; Y = yes.