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. Author manuscript; available in PMC: 2014 Jun 1.

Published in final edited form as: J Oral Maxillofac Surg. 2013 Feb 1;71(6):1017–1026. doi: 10.1016/j.joms.2012.11.016

Histological assessment of intra-cortical bone formation rate in the alveolar region of the mandible. Labeled osteon number (A) and bone formation rate (B) were assessed in the alveolar bone adjacent to the extraction site by measuring fluorochrome labels injected at the end of the experiment. Both parameters were significantly lower at both 4 and 8 weeks post-healing in ZOL and ZOL+DEX groups compared to both CON and DEX groups. p < 0.05 versus CON-treatment within time point (*) or versus DEX- treatment within time point (^).

Histological assessment of intra-cortical bone formation rate in the alveolar region of the mandible. Labeled osteon number (A) and bone formation rate (B) were assessed in the alveolar bone adjacent to the extraction site by measuring fluorochrome labels injected at the end of the experiment. Both parameters were significantly lower at both 4 and 8 weeks post-healing in ZOL and ZOL+DEX groups compared to both CON and DEX groups. p < 0.05 versus CON-treatment within time point (*) or versus DEX- treatment within time point (^).