Table 2.
Change From Baseline to 12 Months in Physical Function, Strength, and Power by Exercise Groupa
Placebo (n = 22 PRT and 25 No PRT) |
Any-T (n = 49 PRT and 47 No PRT) |
Δ Change (95% CI) | P Value | |||
---|---|---|---|---|---|---|
Baseline | Change | Baseline | Change | |||
PRT | ||||||
Physical function (Range 0–100) | ||||||
CS-PFP total | 69.1 ± 9.9 | 3.6 ± 8.0 | 70.5 ± 14.6 | 3.3 ± 7.4 | −0.2 (−4.2, 3.8) | .93 |
Upper body strength | 75.8 ± 10.8 | 1.8 ± 10.9 | 78.6 ± 14.8 | 0.3 ± 11.5 | −0.7 (−6.1, 4.6) | .79 |
Upper body flexibility | 78.2 ± 12.2 | −2.2 ± 11.0 | 75.4 ± 12.7 | 0.9 ± 9.7 | 2.3 (−2.6, 7.1) | .36 |
Lower body strength | 64.1 ± 11.8 | 4.4 ± 9.4 | 67.3 ± 15.9 | 3.5 ± 9.4 | −0.5 (−5.5, 4.4) | .84 |
Balance | 68.9 ± 10.8 | 4.7 ± 8.8 | 69.7 ± 15.3 | 4.6 ± 7.8 | 0.2 (−4.1, 4.5) | .93 |
Endurance | 69.0 ± 10.5 | 4.7 ± 8.6 | 70.0 ± 15.1 | 4.5 ± 7.5 | 0.1 (−4.0, 4.3) | .95 |
Stair climb speed, s | 4.8 ± 1.1 | −0.0 ± 0.9 | 4.7 ± 1.7 | −0.2 ± 0.8 | −0.3 (0.7, 0.1) | .16 |
6-min walk, m | 536.4 ± 65.0 | 24.3 ± 88.8 | 560.1 ± 132.6 | 25.6 ± 79.2 | 3.2 (−39.5, 46.0) | .88 |
Strength (1-RM, kg) | ||||||
Upper body | ||||||
Bench press | 58.4 ± 17.7 | 26.9 ± 11.4 | 58.7 ± 15.9 | 25.7 ± 14.5 | −1.5 (−8.7, 5.6) | .67 |
Incline press | 50.7 ± 15.4 | 24.9 ± 12.5 | 50.6 ± 14.6 | 23.6 ± 12.7 | −1.9 (−8.5, 4.8) | .58 |
Overhead pulldown | 80.5 ± 20.2 | 28.7 ± 14.9 | 79.0 ± 16.6 | 26.2 ± 15.6 | −3.4 (−11.3, 4.6) | .41 |
Seated row | 53.8 ± 14.3 | 21.3 ± 13.1 | 53.6 ± 12.3 | 20.6 ± 11.3 | −1.4 (−7.6, 4.7) | .65 |
Avg upper body | 61.0 ± 15.6 | 25.5 ± 11.3 | 60.5 ± 14.0 | 24.3 ± 11.6 | −1.5 (−7.5, 4.5) | .63 |
Grip strength | 41.7 ± 10.9 | 3.4 ± 6.7 | 40.5 ± 11.0 | 3.2 ± 10.3 | −1.9 (−6.3, 2.5) | .40 |
Lower body | ||||||
Knee extension | 65.6 ± 23.8 | 30.1 ± 18.8 | 63.1 ± 20.2 | 31.5 ± 15.2 | 0.5 (−8.0, 9.0) | .90 |
Knee flexion | 47.6 ± 14.6 | 20.8 ± 11.3 | 49.4 ± 12.2 | 18.5 ± 12.0 | −2.6 (−8.3, 3.2) | .38 |
Seated leg press | 135.7 ± 43.9 | 31.8 ± 27.8 | 129.3 ± 35.4 | 38.3 ± 30.5 | −0.1 (−14.0, 13.7) | .99 |
Avg lower body | 83.9 ± 27.1 | 27.0 ± 17.0 | 80.3 ± 20.3 | 28.0 ± 19.7 | −1.6 (−10.9, 7.7) | .74 |
Power (Power Rig, watts) | ||||||
Leg extensor | 229.3 ± 50.8 | 24.3 ± 62.0 | 245.3 ± 68.8 | 5.1 ± 51.1 | −18.1 (−46.7, 10.5) | .21 |
No PRT | ||||||
Physical function (Range 0–100) | ||||||
CS-PFP total | 68.4 ± 16.1 | 3.1 ± 6.7 | 71.6 ± 11.9 | 0.8 ± 7.3 | −2.2 (−5.8, 1.4) | .23 |
Upper body strength | 75.2 ± 14.2 | 3.6 ± 9.0 | 77.2 ± 12.8 | 0.0 ± 8.8 | −3.5 (−7.9, 0.8) | .11 |
Upper body flexibility | 76.5 ± 11.8 | −2.4 ± 9.5 | 78.6 ± 9.6 | −2.1 ± 9.2 | 0.7 (−3.8, 5.1) | .76 |
Lower body strength | 64.3 ± 18.2 | 5.4 ± 7.0 | 68.4 ± 14.2 | 0.7 ± 8.7 | −4.5 (−8.7, −0.4) | .03 |
Balance | 68.5 ± 17.5 | 2.5 ± 7.4 | 71.7 ± 12.5 | 1.4 ± 7.8 | −0.8 (−4.6, 3.0) | .68 |
Endurance | 68.2 ± 17.0 | 2.8 ± 7.8 | 71.8 ± 12.3 | 1.5 ± 7.5 | −1.1 (−4.9, 2.7) | .57 |
Stair climb speed, s | 5.0 ± 1.4 | −0.1 ± 0.9 | 4.7 ± 1.2 | 0.1 ± 1.0 | 0.1 (−0.4, 0.5) | .78 |
6-min walk, m | 536.1 ± 106.0 | 7.5 ± 93.7 | 564.5 ± 89.1 | 8.5 ± 64.9 | 0.8 (−39.0, 40.6) | .97 |
Strength (1-RM, kg) | ||||||
Upper body | ||||||
Bench press | 56.5 ± 19.8 | 3.5 ± 8.9 | 60.1 ± 15.8 | 7.3 ± 9.2 | 4.7 (0.5, 9.0) | .03 |
Incline press | 50.9 ± 19.2 | 1.9 ± 7.9 | 52.0 ± 15.0 | 8.1 ± 8.9 | 6.9 (2.7, 11.1) | .001 |
Overhead pulldown | 77.4 ± 23.0 | 6.3 ± 11.0 | 82.5 ± 15.5 | 9.3 ± 9.6 | 3.9 (−1.2, 8.9) | .13 |
Seated row | 50.5 ± 12.5 | 5.7 ± 7.4 | 56.1 ± 11.9 | 7.0 ± 9.6 | 2.4 (−1.9, 6.6) | .27 |
Avg upper body | 58.8 ± 17.3 | 4.3 ± 7.7 | 62.8 ± 13.2 | 7.8 ± 6.9 | 3.9 (0.5, 7.4) | .03 |
Grip strength | 56.5 ± 19.8 | 2.9 ± 8.0 | 39.1 ± 12.7 | 6.0 ± 12.4 | 4.1 (0.0, 8.3) | .05 |
Lower body | ||||||
Knee extension | 60.1 ± 25.3 | 11.0 ± 10.1 | 64.9 ± 20.4 | 12.4 ± 10.6 | 1.9 (−3.1, 6.9) | .45 |
Knee flexion | 46.1 ± 11.8 | 5.5 ± 5.6 | 49.0 ± 10.3 | 7.1 ± 7.4 | 1.8 (−1.6, 5.2) | .30 |
Seated leg press | 125.7 ± 38.8 | 9.1 ± 21.5 | 130.4 ± 35.0 | 11.6 ± 23.7 | 4.5 (−6.3, 15.3) | .41 |
Avg lower body | 77.3 ± 23.7 | 9.4 ± 11.6 | 81.8 ± 20.6 | 10.5 ± 10.9 | 1.9 (−3.4, 7.3) | .48 |
Power (Power Rig, watts) | ||||||
Leg extensor | 212.3 ± 70.6 | 4.5 ± 34.6 | 233.3 ± 64.8 | 0.8 ± 36.9 | −1.5 (−19.1, 16.1) | .87 |
Abbreviation: CI, confidence interval.
Data are mean ± SD. Δ Change = change from baseline (any-T) minus change from baseline (placebo). P values are for placebo vs any-T, conditioned on baseline values.