Figure 5.

Manhattan Plot of Analysis of Multiple Smoking Behaviors

$-{\text{log}}_{10}$p values from the 1-DF scaled common effect test SMAT for all SNPs passing quality control. Analysis was performed on both affected $\left(n_1=696\right)$ and control $\left(n_0=730\right)$ ever-smokers with the use of $\pi =0.000745$ to determine the weights and an unstructured working correlation matrix.