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The rs1051730 variant is associated with CHRNA5 expression. The minor allele homozygote of rs1051730, a synonymous single nucleotide polymorphism located in CHRNA3, is associated with lower brain expression of CHRNA5 in (a) brain and (b) peripheral blood mononuclear cells (PBMC). The y-axis represents relative gene expression and the x-axis represents the genotype.
