Table 1.
Top 50 medication-problem associations in the UT data according to the chi-square measure of interestingness.
| Rank | Medication | Problem | Support | Confidence | Chi-square | Interest |
|---|---|---|---|---|---|---|
| 1 | Permethrin | Scabies | 231 | 63.64% | 146,662.62 | 873.66 |
| 2 | Griseofulvin Microsize | Tinea Capitis | 218 | 75.17% | 84,855.09 | 222.67 |
| 3 | BeneFIX | Factor IX Deficiency | 9 | 100.00% | 81,799.76 | 2,820.90 |
| 4 | Glucagon Emergency | Type I Diabetes Mellitus – Uncontrolled | 222 | 52.86% | 72,227.04 | 320.95 |
| 5 | Levothyroxine Sodium | Hypothyroidism | 3016 | 52.67% | 64,909.58 | 20.91 |
| 6 | MetroNIDAZOLE | Bacterial Vaginosis | 1272 | 27.43% | 62,391.93 | 159.69 |
| 7 | Isoniazid | Latent Tuberculosis | 106 | 34.75% | 59,105.14 | 1,038.86 |
| 8 | AquADEKs | Pancreatic Insufficiency | 6 | 60.00% | 55,814.26 | 5,472.60 |
| 9 | LevOCARNitine | Disorder Of Mitochondrial Metabolism | 87 | 31.64% | 55,294.08 | 1,336.34 |
| 10 | Terconazole | Vaginal Candidiasis | 454 | 36.15% | 54,906.72 | 196.20 |
| 11 | Phenex-2 | Phenylketonuria | 8 | 100.00% | 54,064.82 | 1,386.44 |
| 12 | Lupron Depot-Ped | Precocious Puberty | 37 | 69.81% | 54,000.47 | 614.33 |
| 13 | Glucagon Emergency | Visit For: Fit/Adjust Insulin Pump | 119 | 28.33% | 53,420.80 | 1,138.34 |
| 14 | Pyridostigmine Bromide | Myasthenia Gravis | 45 | 58.44% | 52,869.76 | 691.21 |
| 15 | Levemir FlexPen | Taking Medication For Diabetes Long-term Use Of Insulin | 251 | 41.97% | 51,531.66 | 230.30 |
| 16 | Copaxone | Multiple Sclerosis | 406 | 84.06% | 50,619.37 | 34.39 |
| 17 | Truvada | HIV Infection | 230 | 65.71% | 50,189.30 | 97.14 |
| 18 | Solu-CORTEF | Congenital Adrenal Hyperplasia | 25 | 40.98% | 49,986.43 | 2,259.92 |
| 19 | Mestinon | Myasthenia Gravis | 39 | 62.90% | 49,321.72 | 599.05 |
| 20 | Viagra | Male Erectile Disorder | 528 | 36.26% | 47,376.32 | 125.76 |
| 21 | Mebendazole | Enterobiasis (Pinworm) | 27 | 23.89% | 47,210.21 | 5,491.60 |
| 22 | Nystatin | Oral Thrush | 676 | 22.21% | 46,168.09 | 249.56 |
| 23 | Methotrexate | Rheumatoid Arthritis | 479 | 41.29% | 43,468.27 | 90.07 |
| 24 | Riboflavin | Disorder Of Mitochondrial Metabolism | 37 | 55.22% | 41,071.64 | 568.33 |
| 25 | Norvir | HIV Infection | 186 | 65.49% | 40,439.78 | 78.56 |
| 26 | Elmiron | Chronic Interstitial Cystitis | 25 | 36.23% | 40,438.36 | 1,893.11 |
| 27 | NovoLOG FlexPen | Taking Medication For Diabetes Long-term Use Of Insulin | 258 | 32.09% | 40,406.22 | 236.72 |
| 28 | Synthroid | Hypothyroidism | 2154 | 45.91% | 39,694.00 | 14.93 |
| 29 | Coenzyme Q10 | Disorder Of Mitochondrial Metabolism | 53 | 34.42% | 36,636.56 | 814.09 |
| 30 | Permethrin Lice Treatment | Pediculosis Capitis | 8 | 66.67% | 36,038.43 | 1,386.44 |
| 31 | Ergocalciferol | Vitamin D Deficiency | 449 | 55.78% | 35,955.42 | 36.17 |
| 32 | Kaletra | HIV Infection | 159 | 67.66% | 35,716.97 | 67.16 |
| 33 | Griseofulvin Ultramicrosize | Tinea Capitis | 92 | 74.80% | 35,607.94 | 93.97 |
| 34 | Pen Needles 5/16” | Taking Medication For Diabetes Long-term Use Of Insulin | 192 | 37.14% | 34,822.13 | 176.16 |
| 35 | Levemir FlexPen | Diabetes Mellitus Poorly Controlled | 342 | 57.19% | 34,308.87 | 40.88 |
| 36 | Atripla | HIV Infection | 154 | 66.67% | 34,081.10 | 65.04 |
| 37 | Gris-PEG | Tinea Capitis | 88 | 73.95% | 33,671.50 | 89.89 |
| 38 | Floxin Otic | Chronic Tubotympanic Suppurative Otitis Media | 89 | 31.79% | 33,475.92 | 476.02 |
| 39 | Pen Needles 5/16” | Diabetes Mellitus Poorly Controlled | 309 | 59.77% | 32,413.11 | 36.94 |
| 40 | Reyataz | HIV Infection | 139 | 69.85% | 32,239.37 | 58.71 |
| 41 | Colistimethate Sodium | Pseudomonas Wound Infection | 12 | 17.14% | 31,883.98 | 10,945.20 |
| 42 | Methimazole | Graves’ Disease | 108 | 32.24% | 31,398.06 | 336.18 |
| 43 | Zolpidem Tartrate | Insomnia | 927 | 28.58% | 31,389.00 | 53.16 |
| 44 | Cialis | Male Erectile Disorder | 312 | 40.36% | 31,148.37 | 74.31 |
| 45 | Warfarin Sodium | Atrial Fibrillation | 695 | 28.62% | 30,999.96 | 67.78 |
| 46 | Malathion | Pediculosis Capitis | 6 | 75.00% | 30,408.46 | 1,039.83 |
| 47 | Polyethylene Glycol 3350 | Constipation | 753 | 41.93% | 29,477.84 | 26.59 |
| 48 | Carbidopa-Levodopa | Parkinson’s Disease | 186 | 46.50% | 29,062.92 | 81.00 |
| 49 | Vitamin D (Ergocalciferol) | Vitamin D Deficiency | 374 | 54.05% | 28,984.88 | 30.13 |
| 50 | NovoLOG FlexPen | Diabetes Mellitus Poorly Controlled | 361 | 44.90% | 28,299.94 | 43.15 |