Table 4.
Hormone | Baseline
|
Percentage change from baseline to month 1
|
||||
---|---|---|---|---|---|---|
PSA responders | PSA nonresponders | P* | PSA responders | PSA nonresponders | P* | |
Patients, n | 20 | 21 | 14 | 16 | ||
Androstenedione (ng/mL) | 0.82 (0.6, 1.18) | 0.85 (0.63, 0.98) | 0.98 | −58 (−73, −43) | −56 (−77, −45) | 0.82 |
DHEAS (ng/mL) | 840 (397, 1,145) | 480 (311, 1,491) | 0.56 | −93 (−95, −85) | −85 (−91, −61) | 0.1 |
Testosterone (ng/mL) | 0.33 (0.26, 0.50) | 0.39 (0.23, 0.47) | 0.91 | −66 (−74, −56) | −61 (−70, −49) | 0.29 |
DHT† (pg/mL) | 2.3 (<2.0, 3.7) | 3 (<2.0, 4.0) | 0.63 |
NOTE: Median and interquartile range (25th, 75th percentiles).
P value by Wilcoxon rank-sum test comparing PSA responders versus PSA nonresponders.
For DHT, at baseline, n = 16 and 17 for PSA responders and nonresponders, respectively, and n = 16 and 15 for percent change from baseline to month 1, respectively.