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. Author manuscript; available in PMC: 2013 May 6.
Published in final edited form as: Chem Soc Rev. 2011 Apr 13;40(12):5771–5788. doi: 10.1039/c1cs15014f

Fig. 20.

Fig. 20

Left: illustration of the Invader LNA concept. Right: time course of steady-state fluorescence spectra upon addition of pre-annealed Invader LNA to pre-annealed isosequential dsDNA target (λex = 335 nm, 20 °C). Invader LNA: 5'-d(GGT A38A TAT AGG C):3'-d(CCA TA38 ATA TCC G) using monomer 38. Isosequential dsDNA target: as for Invader LNA except 38 is placed by T. (Adapted from ref. 135. Copyright 2010 RSC Publishing).