Table 1.
Summary of investigations
| Variable | Reference range (adults) | Day 1 | Day 3 | Day 7 |
|---|---|---|---|---|
| Haematocrit (%) | 0.36–0.46 | 0.543 | 0.429 | 0.231 |
| Haemoglobin (g/dl) | 11.5–16.0 | 17.6 | 14.2 | 7.7 |
| WCC (×109/l) | 4.0–10.5 | 30.75 | 25.77 | 20.91 |
| Differential count (×109/l) | ||||
| Neutrophils | 1.8–7.5 | 24.81 | 21.38 | 18.80 |
| Lymphocytes | 1.3–4.0 | 3.44 | 1.82 | 0.88 |
| Monocytes | 0.2–0.8 | 2.31 | 2.56 | 1.21 |
| Eosinophils | 0.02–0.4 | 0.14 | 0.01 | 0.00 |
| Basophils | 0.0–0.20 | 0.06 | 0.01 | 0.03 |
| Platelet count (×109/l) | 145–400 | 120 | 60 | 65 |
| Mean corpuscular volume (fl) | 80.0–101.0 | 96.5 | 95.1 | 96.2 |
| Lactate dehydrogenase (IU/l) | 313–618 | 1284 | ||
| Sodium (mmol/l) | 134–145 | 128 | 133 | 131 |
| Potassium (mmol/l) | 3.6–5.3 | 3.6 | 4.9 | 4.4 |
| Urea (mmol/l) | 2.8–7.0 | 16.9 | 10.9 | 13.4 |
| Creatine (umol/l) | 44–80 | 192 | 108 | 98 |
| Creatine kinase (IU/l) | < 135 | 4014 | 12113 | |
| Glucose (mmol/l) | 2.7–11.0 | 20.7 | ||
| Corrected calcium (mmol/l) | 2.1–2.55 | 2.27 | 2.60 | |
| Thyroid-stimulating hormone (mU/l) | 0.27–4.2 | 1.39 | ||
| Albumin (g/l) | 35–49 | 22 | 16 | 19 |
| Amylase (IU/l) | 30–110 | 236 | ||
| Lactate (mmol/l) | 0.5–1.6 | 12.0 | ||
| Rheumatological tests | ||||
| Serum κ light chains | High levels | |||
| Serum immunofixation | Presence of an IgG κ paraprotein | |||
| C3 | Low | |||
| C4 | Normal | |||
| C4 esterase inhibitor | Normal | |||
| Mast cell tryptase | Sample lost in transport to reference laboratory | |||
| Antinuclear antibody | Negative | |||
| Myeloperoidase | Negative | |||
| Proteinase 3 | Negative | |||
| ANCAIF | Negative | |||
| Antiglomerular basement membrane antibody | Negative | |||
| Rheumatoid factor | Negative | |||