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. Author manuscript; available in PMC: 2014 Apr 15.
Published in final edited form as: Cancer Res. 2013 Feb 19;73(8):2435–2444. doi: 10.1158/0008-5472.CAN-12-3381

Figure 3. Elevated levels of immunosuppressive cytokines in HCC patients.

Figure 3

(A–C) Cytokine-specific sandwich ELISA of plasma from HCC patients and healthy normal subjects were assayed in order to measure levels of circulating IFN-γ, IL-10, and TGF-β1. (D) Correlation of TGF-β1 plasma levels and frequency of CD4+Foxp3+ Tregs. Each symbol represents an individual HCC patient (Inline graphic) or normal healthy subjects (Inline graphic); lines represent median values for the group. ** P < 0.01, *** P < 0.001, Mann-Whitney U test; † P < 0.05 Hochberg adjustment for multiple comparison.