Table 1.
Patient characteristics | HCC (n=23) | Normal Healthy (n=20) |
---|---|---|
Gender (M:F) | 16:7 | 10:10 |
Median age (yrs) | 64 (40–82) | |
Child Pugh Class Liver function | A = 16 | − |
B = 7 | ||
C = 0 | ||
BCLC class | A = 0 | − |
B = 21 | ||
C = 2 | ||
D = 0 | ||
Etiology of liver disease | Hepatitis B = 1 | − |
Hepatitis C = 13 | ||
Hepatitis B and C = 1 | ||
Alcohol = 2 | ||
No known risk factor = 6 | ||
Prior therapies (some patients had more than one therapy hence numbers ≠ 23) | None = 10 | − |
Locoregional = 8 | ||
Chemotherapy or biologic therapy = 7 | ||
Liver resection = 4 |
For the stimulation assays 8 patients were chosen. Of those patients 5 are alive, median follow up time is 15 months (range 12–25 months) and of the 3 patients who have died, median survival was 7 months (range 2–10 months). The patients had BCLC class B (n=7) or C (n=1) liver function and Child Pugh class A (n=6) or class B (n=2) liver function. The etiology of cirrhosis was chronic hepatitis C (n=4) and neither hepatitis HBV or HCV (n=4).