Activity and selectivity of the Cox2 promoter in PDAc. Human PDAc cell lines (S2O13, S2VP10, ASPC-1, MiaPaCa-2), Cox2-positive (A549), and Cox2-negative (BT474) cell lines were infected with AdCMVLuc or Ad-Cox2Luc. Luc activity was measured 2 days after infection. Data are shown as percentages of relative light units normalized to AdCMVLuc activity. The Cox2 promoters exhibited high levels of activity in all PDAc cell lines under investigation.