Skip to main content
. Author manuscript; available in PMC: 2013 May 6.
Published in final edited form as: Lab Chip. 2011 Jun 6;11(14):2385–2396. doi: 10.1039/c1lc20170k

Fig. 7.

Fig. 7

Time response of the drug effect on the nematodes in the drug well. (a) Box plot of the total time from initial exposure of 100 μM levamisole to unresponsiveness for O. dentatum and L4 stage C. elegans. Median times for restraint strains (LEVR median = 8.5 min; lev-8 median = 3.750 min) were found to be significantly higher than the median times of their sensitive counterparts (SENS median = 3.7 min; N2 median = 0.4 min). (b) [scale bar = ~200 μm] Time-lapsed images of SENS O. dentatum being exposed to 100 μM levamisole in the drug well. The drug effect is tracked on a particular nematode (indicated with an arrow). The worm is able to move freely in the initial 120 s, after which time the drug begins to render the worm unresponsive within the next 120 s.