Table 1.
Normal control n = 20 |
Histological activity of UC |
Types of UC |
UC with dysplasia n = 10 | ||||
Inactive n = 10 | Mild-moderate n = 30 | Severe n = 34 | Initial n = 30 | Chronic n = 44 | |||
Gender (n) | |||||||
Male | 14 | 5 | 16 | 22 | 16 | 27 | 6 |
Female | 6 | 5 | 14 | 12 | 14 | 17 | 4 |
Mean age3, yr | 40.6 ± 12.5 | 41.2 ± 13.3 | 44.7 ± 13.2 | 43.2 ± 17.1 | 42.8 ± 17.3 | 46.5 ± 13.6 | 44.7 ± 16.6 |
Mean duration of disease3, yr | - | 6.14 ± 4.2 | 4.3 ± 2.3 | 3.7 ± 3.1 | 0.8 ± 0.6 | 5.1 ± 0.61 | 10.5 ± 1.42 |
Extent of disease (n) | |||||||
Extensive colitis | - | 0 | 8 | 19 | 8 | 19 | 3 |
Left-side colitis | - | 4 | 13 | 9 | 13 | 13 | 4 |
Proctitis | - | 6 | 9 | 6 | 9 | 12 | 3 |
Treatment (n) | |||||||
Aminosalicylates | - | 8 | 25 | 20 | 16 | 35 | 5 |
Corticosteroids | - | 4 | 5 | 18 | 4 | 15 | 3 |
Immunosuppressive agent | - | 0 | 0 | 1 | 0 | 1 | 0 |
Biological agent | - | 0 | 0 | 0 | 0 | 0 | 0 |
None | - | 3 | 2 | 0 | 10 | 5 | 2 |
The mean duration of disease in the chronic group (5.1 ± 0.6 years) was significantly longer than in the initial group (0.8 ± 0.6 years; P < 0.001);
The mean duration of disease in the ulcerative colitis (UC) with dysplasia group (10.5 ± 1.4 years) was significantly longer than in other groups (P < 0.05);
Data are expressed as mean ± SD.