Table 2.
Treatment effect on time to first primary endpoint, components of the primary endpoint, and other events for Vascular Surgeons (n=1002).
| Periprocedural Period | Four-year Period | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| CAS # events (rate ± SE) | CEA # events (rate ± SE) | Hazard Ratio (95% CI) | P-value | CAS # events (rate ± SE) | CEA # events (rate ± SE) | Hazard Ratio (95% CI) | P-value | ||
| MI Endpoint | Overall | 3 (1.3 ± 0.7) | 20 (2.6 ± 0.6) | 0.48a (0.14 – 1.62) | 0.24 | ||||
| Symptomatic | 2 (2.4 ± 1.7) | 10 (2.6 ± 0.8) | 0.93 a (0.20 – 4.25) | 0.93 | |||||
| Asymptomatic | 1 (0.6 ± 0.6) | 10 (2.6 ± 0.8) | 0.25 a (0.03 – 1.91) | 0.18 | |||||
| Stroke and Death Endpoint (any stroke or death within periprocedural period and post-procedural ipsilateral stroke) | Overall | 9 (3.8 ± 1.2) | 9 (1.2 ± 0.4) | 3.94 (1.53 – 10.10) | 0.004 | 14 (6.2 ± 1.6) | 20 (3.1 ± 0.7) | 2.76 (1.37 – 5.55) | 0.004 |
| Symptomatic | 5 (6.1 ± 2.6) | 5 (1.3 ± 0.6) | 4.84 a (1.40 – 16.74) | 0.013 | 6 (7.4 ± 2.9) | 13 (3.8 ± 1.1) | 2.45 (0.92 – 6.48) | 0.07 | |
| Asymptomatic | 4 (2.6 ± 1.3) | 4 (1.1 ± 0.5) | 2.50 a (0.63 – 9.99) | 0.20 | 8 (5.6 ± 2.0) | 7 (2.4 ± 1.0) | 3.10 (1.12 – 8.59) | 0.03 | |
| Primary Endpoint (any stroke, MI or death within periprocedural period and post-procedural ipsilateral stroke) | Overall | 10 (4.2 ± 1.3) | 29 (3.8 ± 0.7) | 1.26 (0.61 – 2.60) | 0.54 | 14 (6.2 ± 1.6) | 39 (5.6 ± 0.9) | 1.30 (0.70 – 2.41) | 0.41 |
| Symptomatic | 6 (7.3 ± 2.9) | 15 (3.9 ± 1.0) | 2.01 (0.78 – 5.20) | 0.15 | 6 (7.3 ± 2.9) | 22 (6.1 ± 1.3) | 1.36 (0.55 – 3.38) | 0.50 | |
| Asymptomatic | 4 (2.6 ± 1.3) | 14 (3.7 ± 1.0) | 0.75 (0.24 – 2.29) | 0.62 | 8 (5.6 ± 2.0) | 17 (5.1 ± 1.3) | 1.25 (0.54 – 2.89) | 0.61 | |
a
Univariate proportional hazards model employed because of the small number of events.
CAS=carotid artery stenting; CEA=carotid endarterectomy; SE=standard error; CI=confidence interval.