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. 2013 Mar 27;14(4):6920–6959. doi: 10.3390/ijms14046920

Figure 8.

Figure 8

Details of the “flavin out” (MICAL-MOox) and “flavin in” (MICAL-MOred) conformations of MICAL-MO highlighting the conserved residues forming the tunnel leading to the active site in the “flavin in” conformation. The residues in the conserved regions surrounding the FAD isoalloxazine ring (arrows) and comprising residues 121–130, 278–300 and 390–405 (red stars in Figure 4) are shown. The views correspond to those shown in Figure 7. Color code is also as in Figure 7 except for FAD that is in sticks and yellow. The CCP4MG program was used to generate the figure [72].