Table 1.

Summary of MICAL sequences as retrieved from databanks. The identification was done by taking into account annotations and direct sequence comparisons. When several isoforms for each one of the predicted proteins exist on the basis of alternative splicing and comparison of cDNA and DNA clones deposited in databanks, the putative full-length protein was selected following sequence comparisons within and among the MICAL1–3 classes using BLAST and ClustalW2 or Clustal Omega [61]. The accession codes of isoforms are given in a few instances.

Protein	Organism	Chromosome location	Nucleotide	Protein	Length (residues)	Gene ID	UniPro/SwissProt	Remarks
MICAL1	human	6q21	NM_022765	NP_073602	1067	64780	Q8TDZ2	Figure 4
MICAL2	human	11p15	NM_014632	NP_055447	1124	9645	O94851	Figure 4
MICAL3	human	22q11.21	NM_015241	NP_056056	2002	57553	Q7RTP6	Figure 4
MICAL1	mouse	10 B1-B2	NM_138315	NP_612188	1048	171580	Q8VDP3	Figure 4
MICAL2	mouse	7E3	NM_001193305	NP_001180234	1102	320878	8QBML1	isoform A; Figure 4
MICAL3	mouse	6F1	NM_001270475	NP_001257404	1993	194401	Q8CJ19	isoform 1; Figure 4
MICAL1	rat	20q12	NM_001106397	NP_001099867	1047	294520	D3ZBP4	Figure 4
MICAL2	rat	1q33		EDM_17817	1103	365352	D4A1F2-2	Figure 4
MICAL3	rat	4q42	NM_001191085	NP_001178014	1997	362427	-	Figure 4
MICAL1	guinea pig	-	XM_003466042	XP_003466090	1058	100715118	H0V032	Figure4
MICAL2	guinea pig	-	XM_003465749	XP_003465749	1105	100735168	-	Figure 4
MICAL3	guinea pig	-	XM_003461762	XP_003461810	2005	100726239		Figure 4
MICAL1	macaque	4	XM_002803949	XP_002803995	1065	698737		Figure 4
MICAL2	macaque	14		EEH23095	1124	701439		Figure 4
MICAL3	macaque	10	XM_001103660	XP_001103660	2001	710292		Figure 4
MICAL1	D. rerio	23	XM_003201226	XP_003201274	1214	568573	E7F9T0	Predicted as MICAL3, Figure 4
MICAL2	D. rerio	25	JX291155	AFS28884	1120	569564		Figure 4
MICAL3	D. rerio	18			1994	567456	F1QH17.2	Authentic according to UniPro; Figure 4
MICAL	drosophila	3R	AF520715	AAM55244	4723	41225	Q86BA1	long isoform differing from others for interdomain regions; Figure 4