Skip to main content
. 2013 Mar 27;14(4):6920–6959. doi: 10.3390/ijms14046920

Table 4.

Inhibition of the human MICAL-MO NADPH oxidase activity by NADP+ and EGCG. Assays were carried out at 25 °C in the presence of the indicated NAD(P)H concentration ranges and additions in 20 mM Hepes/KOH buffer, pH 7.0. Other conditions are as in Table 2. Data are from [70].

NADPH, μM Inhibitor, μM NaCl, M KM, μM kcat, s−1 Ki, μM
15–160 NADP+, 0–0.15 0 24.3 ± 2.1 3.6 ± 0.1 77 ± 8
0–100 EGCG, 0–50 - 25 ± 2 3.9 ± 0.1 17 ± 0.6