Table 1.
Mean (SD) values for selected clinical variables by group
| HC (n = 49) |
MCI (n = 60) |
AD (n = 146) |
|
|---|---|---|---|
| Gender (male/female) | 17/32 | 16/44 | 39/107 |
| Age (years) | 66.1 (8.0) | 76.1 (9.2)a | 79.1 (8.0)a,d |
| MMSE (score out of 30) | 29.1 (1.2) | 24.6 (4.1)a | 19.1 (5.1)a,b |
| ADAS-J cog (score out of 70) | 3.5 (1.6) | 10.7 (6.1)a | 19.2 (8.1)a,b |
| CDT-command (score out of 10) | 9.5 (0.9) | 7.6 (2.7)a | 5.6 (2.7)a,b |
| CDT-copy (score out of 10) | 10.0 (0.2) | 9.7 (0.7) | 8.2 (2.3)a,b |
Notes:
a
P < 0.001 versus HC;
b
P < 0.001 versus MCI;
c
P < 0.05 versus HC;
d
P < 0.05 versus MCI.
Abbreviations: SD, standard deviation; HC, healthy controls; n, number; MCI, mild cognitive impairment; AD, Alzheimer’s disease; MMSE, Mini-Mental State Exam; ADAS-J cog, Japanese version of the Alzheimer’s Disease Assessment Scale-cognitive subscale; CDT, clock drawing test.