Table 2.
Mean (SD) ANCOVA values
| HC (n = 49) |
MCI (n = 60) |
AD (n = 146) |
|
|---|---|---|---|
| Adjusted for age and gender | |||
| MMSE | 28.1 (0.7) | 24.6 (0.5) | 19.4 (0.4)a,b |
| ADAS-J cog | 4.8 (1.0) | 10.7 (0.9)a | 18.7 (0.6)a,b |
| CDT-command | 9.0 (0.4) | 7.6 (0.3)c | 5.8 (0.2)a,b |
| CDT-copy | 10.0 (0.3) | 9.7 (0.2) | 8.2 (0.2)a,b |
Notes:
a
P < 0.001 versus HC;
b
P < 0.001 versus MCI;
c
P < 0.05 versus HC.
Abbreviations: SD, standard deviation; ANCOVA, analysis of covariance; HC, healthy controls; n, number; MCI, mild cognitive impairment; AD, Alzheimer’s disease; MMSE, Mini-Mental State Exam; ADAS-J cog, Japanese version of the Alzheimer’s Disease Assessment Scale-cognitive subscale; CDT, clock drawing test.