Mobility independence within Ltn1’s termini in Maskiton. (a–e) For all masking procedures, the aligned average of the full data set is shown at left, followed by the masked region, and 8 distinct class averages resulting from the masked classification at right. Arrows indicate heterogeneity identified within the outlined/boxed region in the class averages. The aligned dataset was masked with (a) a circular mask to show overall global heterogeneity, (b) an N-terminus mask (left region) to show increased heterogeneity within the C-terminus (right region) of Ltn1, and (c–e) three different C-terminus masks to show increased heterogeneity within the N-terminus of the protein.