Table 1. Sociodemographic Features and the Median Survival Times (Months) of the Fatal Cases of Various Prion Diseases.
| All | Subtype | P a | ||||
| sCJD | fCJD | FFI | GSS | |||
| Gender | ||||||
| Male (n) | 65 | 51 | 8 | 6 | 0 | |
| Median(range) | 7.2(1.0–23.3) | 7.2(1.0–23.3) | 3.0(1.0–8.2) | 8.1(6.1–10.1) | – | 0.005 |
| Female (n) | 56 | 45 | 4 | 6 | 1 | |
| Median(range) | 6.1(1.0–22.4) | 5.1(1.0–22.4) | 3.1(3.0–9.1) | 9.1(8.1–14.2) | 10.1 | 0.671 |
| P b | 0.444 | 0.216 | 0.342 | 0.363 | ||
| Age at onset | ||||||
| <50 (n) | 21 | 10 | 2 | 8 | 1 | |
| Median(range) | 8.2(1.0–22.4) | 5.1(1.0–22.4) | 4.1(4.1–9.1) | 9.1(6.1–14.2) | 10.1 | 0.829 |
| 50–70 (n) | 77 | 68 | 5 | 4 | 0 | |
| Median(range) | 7.1(1.0–23.3) | 7.1(1.0–23.3) | 3.0(2.0–5.0) | 8.1(8.1–10.1) | – | 0.001 |
| >70 (n) | 23 | 18 | 5 | 0 | 0 | |
| Median(range) | 6.0(1.0–21.3) | 4.1(1.0–21.3) | 7.1(1.0–8.2) | – | – | 0.258 |
| P | 0.742 | 0.819 | 0.110 | 0.369 | ||
Abbreviations: sCJD = sporadic Creutzfeldt-Jakob disease; fCJD = familial CJD; GSS = Gerstmann-straussler-Sheinker syndrome; FFI = fatal familial insomnia.
a
Difference in median survival time among multiple-group were tested by using Breslow (Wilcoxon) method.
b
Difference in median survival time between two groups were tested by using log-rank (Mantel-Cox) method.