Table 2. Clinical Examinations and the Median Survival Times (Months) of the Fatal Cases of Various Prion Diseases.
| All | Subtype | P | ||||
| sCJD | fCJD | FFI | GSS | |||
| PSWCa on EEGb | ||||||
| Positive (n) | 58 | 54 | 3 | 0 | 1 | |
| Median(range) | 6.1(1–22.4) | 6.1(1–22.4) | 5.0(1.0–8.2) | – | 10.1 | 0.410 |
| Negative (n) | 22 | 7 | 4 | 11 | 0 | |
| Median(range) | 8.1(2.1–14.2) | 5.0(2.1–9.1) | 3.0(2.1–7.1) | 9.1(6.1–14.2) | – | 0.001 |
| P | 0.331 | 0.223 | 0.488 | |||
| MRIc | ||||||
| Typical (n) | 40 | 36 | 4 | 0 | 0 | |
| Median(range) | 5.1(1.0–19.3) | 6.1(1.0–19.3) | 2.1(2.0–3.1) | – | – | <0.001 |
| Atypical (n) | 60 | 45 | 5 | 10 | 0 | |
| Median(range) | 8.1(1.0–21.3) | 7.1(1.0–21.3) | 7.1(3.0–9.1) | 9.1(8.1–14.2) | – | 0.362 |
| P | 0.081 | 0.211 | 0.022 | |||
| 14-3-3 | ||||||
| Positive (n) | 90 | 76 | 8 | 6 | 0 | |
| Median(range) | 6.1(1.0–23.3) | 6.1(1.0–23.3) | 3.0(1.0–8.2) | 8.1(6.1–10.1) | – | 0.002 |
| Negative (n) | 27 | 17 | 4 | 6 | 0 | |
| Median(range) | 8.1(2.0–20.3) | 6.1(2.0–20.3) | 7.1(4.1–9.1) | 8.2(8.1–14.2) | – | 0.394 |
| P | 0.832 | 0.943 | 0.080 | 0.505 | – | |
a
Periodic sharp curve complexes.
b
Electroencephalograms.
c
Magnatic Resonance Imaging releases high signal in caudate/putamen.