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. 2013 May 6;8(5):e63180. doi: 10.1371/journal.pone.0063180

Table 2. Genes involved in the oxidative stress response that are differentially expressed under Na+ depleted conditions.

Parent ATCC 33277−/+Na+ rprY mutant −/+Na+
Locusa Common name Fold expb P valc Repeats Fold exp P val Repeats
PG0034 Thioredoxin 2.95 0.0004 12 3.25 0.0001 12
PG0046 Phosphatidate cytidylyltransferase 2.21 0.0028 12 2.25 0.0001 12
PG0047 Cell division protein FtsH, putative 2.04 0.0026 12 2.12 0.0016 12
PG0095 DNA mismatch repair protein MutS 0.65 0.0806 8 1.91 0.0041 8
PG0209 Formate-nitrite transporter 3.71 0.0004 12 3.39 0.0241 11
PG0258 ABC transporter, ATP-binding protein 1.78 0.0028 12 3.94 0.0000 12
PG0275 Thioredoxin family protein 1.71 0.0049 12 4.09 0.0000 12
PG0432 NOL1-NOP2-sun family protein 2.82 0.0517 12 3.58 0.0001 12
PG0433 Tetrapyrrole methylase family protein 2.88 0.0165 12 7.43 0.0001 8
PG0618 Alkyl hydroperoxide reductase, C subunit 1.17 0.1644 12 1.85 0.0119 12
PG0889 Peptidase, M24 family 2.35 0.0004 12 2.94 0.0002 12
PG0890 Alkaline phosphatase, putative 2.37 0.0002 12 3.46 0.0000 12
PG1043 Ferrous iron transport protein B 0.96 0.7002 7 2.01 0.0501 9
PG1044 Iron dependent repressor, putative 1.50 0.2211 12 3.27 0.0067 8
PG1088 Acetyltransferase, GNAT family 2.14 0.0001 12 0.94 0.5204 12
PG1089 DNA-binding response regulator RprY 1.58 0.0001 12 2.05d 0.0000 12
PG1124 ATP:cob(I)alamin adenosyltransferase, putative 1.12 0.4240 12 2.02 0.0000 12
PG1134 Thioredoxin reductase 1.27 0.0248 12 1.93 0.0075 12
PG1190 Glycerate dehydrogenase 1.56 0.1968 12 4.20 0.0000 10
PG1286 Ferritin 2.03 0.0005 12 4.00 0.0000 12
PG1321 Formate–tetrahydrofolate ligase 4.79 0.0001 12 6.78 0.0000 12
PG1545 Superoxide dismutase, Fe-Mn 1.96 0.0069 12 4.44 0.0001 12
PG1640 DNA-damage-inducible protein F 1.60 0.0011 12 2.16 0.0001 10
PG1642 Cation-transporting ATPase, authentic frameshift 1.88 0.0000 12 3.50 0.0000 12
PG1729 Thiol peroxidase 3.03 0.0000 12 3.68 0.0000 12
PG1841 Conserved hypothetical protein 3.20 0.0006 12 4.02 0.0005 12
PG1868 Membrane protein, putative 1.50 0.4660 10 3.83 0.0013 12
PG2008 TonB-dependent receptor, putative 1.03 0.8227 5 3.11 0.0620 8
PG2213 Nitrite reductase-related protein 1.54 0.0004 12 2.26 0.0005 12
a

Loci numbers are those from the annotation of the genome of strain W83 and the microarrays.

b

Fold expression.

c

P values were calculated using LIMMA.

d

The microarray PCR amplicon for rprY is upstream from the erythromycin resistance cassette that was used to generate the rprY mutation, thus an expression signal was still detectable.