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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: J Thorac Oncol. 2013 Feb;8(2):208–213. doi: 10.1097/JTO.0b013e318274592e

Figure 3. Radiation thoracic toxicity and sensitive genotypes in TGFβ1 pathway.

Figure 3

Toxicity grade was determined prospectively per CTCAE 3.0 standard. Presence of any one sensitive genotype (tissue plasminogen activator CC type, or angiotensin converting enzyme D type (DD or DI) or transforming growth factor beta1 (TGFß1) 509CC type) is associated with a significantly higher mean grade of combined radiation induced thoracic toxicity (RITT). Error bars show the standard error of mean. There seems no significant difference in the overall score of RITT in patients with 1, 2, or all 3 high risk variants.