Table 1.
Baseline characteristics of patients
| Variables | PCI-only (n = 6268) | FFR-guided group (n = 1090) |
||
|---|---|---|---|---|
| All (n = 1090) | FFR-Perform (n = 369) | FFR-Defer (n = 721) | ||
| Age (year) | 67.9 ± 11.6* | 65.7 ± 11.3 | 65.5 ± 11.3 | 65.8 ± 11.4 |
| Male gender, n (%) | 4416 (70.4)* | 683 (62.6) | 255 (69.1) | 428 (59.3)‡ |
| Body mass index | 30.2 ± 5.9 | 30.4 ± 5.8 | 30.4 ± 5.7 | 30.4 ± 5.8 |
| Current smoking, n (%) | 836 (13.3) | 140 (12.8) | 49 (13.2) | 91 (12.6) |
| Diabetes mellitus, n (%) | 1862 (29.7) | 306 (28.0) | 106 (28.7) | 200 (27.7) |
| Hypertension, n (%) | 4897 (78.1) | 864 (79.2) | 296 (80.2) | 568 (78.7) |
| Hypercholesterolaemia, n (%) | 5119 (81.6)* | 608 (55.7) | 312 (84.5) | 296 (41.0) |
| Chest pain, n (%) | 4529 (72.2)* | 753 (69.0) | 261 (70.7) | 492 (68.2) |
| Dyspnoea, n (%) | 168 (2.6)* | 89 (8.1) | 5 (1.3) | 84 (11.6)† |
| ACS (1–7 days), n (%) | 818 (13.0)* | 48 (4.4) | 19 (5.1) | 29 (4.0) |
| History of MI (>7 days), n (%) | 1882 (31) | 270 (25) | 99 (27) | 171 (24) |
| Prior PCI, n (%) | 1981 (31.6)* | 445 (40.8) | 168 (45.5) | 277 (38.4)‡ |
| CVD, n (%) | 682 (10.8) | 103 (9.4) | 35 (9.4) | 68 (9.4) |
| PAD, n (%) | 718 (11.4) | 106 (9.7) | 37 (10.0) | 69 (9.5) |
| Chronic obstructive pulmonary disease, n (%) | 704 (11.2) | 121 (11.1) | 32 (8.6) | 89 (12.3) |
| Renal dysfunction, n (%) | 285 (4.5) | 41 (3.7) | 13 (3.5) | 28 (3.8) |
| Stress test, n (%) | 1008 (16.0) | 112 (10.2) | 67 (18.1) | 45 (6.2) |
| LVEF ≤40%, n (%) | 705 (11.2)* | 82 (7.5) | 31 (8.4) | 51 (7.0) |
ACS, acute coronary syndrome; CVD, cerebral vascular disease; FFR, fractional flow reserve; LVEF, left ventricular ejection fraction; MI, myocardial infarction; PCI, percutaneous coronary intervention; PAD, peripheral artery disease.
*P < 0.001 when compared with the FFR-guided group.
†P < 0.05 when compared with the FFR-Perform group.
‡P < 0.001 when compared with the FFR-Perform group.