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. 2013 Jan 23;34(18):1375–1383. doi: 10.1093/eurheartj/eht005

Table 5.

Model estimates after excluding patients with percutaneous coronary intervention deferred in a vessel with a 0.75–0.80 fractional flow reserve measure

Events Adjusteda HR 95% CI P-value
FFR use vs. no FFR
 MACE 0.95 0.83–1.08 0.42
 Death 0.84 0.67–1.04 0.11
 MI 0.75 0.54–1.03 0.08
 Death/revascularization 0.94 0.82–1.08 0.38
 Death/MI 0.80 0.66–0.96 0.02

Deferral of PCI after FFR vs. Perform PCI
 MACE 0.86 0.67–1.11 0.24
 Death 0.73 0.48–1.11 0.14
 MI 0.39 0.20–0.73 0.004
 Death/revascularization 0.89 0.69–1.15 0.36
 Death/MI 0.64 0.45–0.92 0.02

CI, confidential interval; FFR, fractional flow reserve; HR, hazard ratio; MACE, major adverse cardiac events; MI, myocardial infarction; PCI, percutaneous coronary intervention.

aAdjusted for age, sex, body mass index, smoking history (current, former, or never), chronic heart failure on presentation, diabetes, hypertension, hypercholesterolaemia, primary symptom, recent MI, prior PCI, prior coronary artery bypass grafting, history of myocardial infarction, heart failure, cerebral vascular disease, peripheral artery disease, chronic obstructive pulmonary disease, renal dysfunction, presence of tumour/lymphoma/leukaemia, metastatic cancer, ejection fraction ≤40%, ejection fraction unknown, level of stenosis in each coronary vessel (right coronary artery, left anterior descending, left circumflex, left main coronary artery).