Table 5.
Events | Adjusteda HR | 95% CI | P-value |
---|---|---|---|
FFR use vs. no FFR | |||
MACE | 0.95 | 0.83–1.08 | 0.42 |
Death | 0.84 | 0.67–1.04 | 0.11 |
MI | 0.75 | 0.54–1.03 | 0.08 |
Death/revascularization | 0.94 | 0.82–1.08 | 0.38 |
Death/MI | 0.80 | 0.66–0.96 | 0.02 |
Deferral of PCI after FFR vs. Perform PCI | |||
MACE | 0.86 | 0.67–1.11 | 0.24 |
Death | 0.73 | 0.48–1.11 | 0.14 |
MI | 0.39 | 0.20–0.73 | 0.004 |
Death/revascularization | 0.89 | 0.69–1.15 | 0.36 |
Death/MI | 0.64 | 0.45–0.92 | 0.02 |
CI, confidential interval; FFR, fractional flow reserve; HR, hazard ratio; MACE, major adverse cardiac events; MI, myocardial infarction; PCI, percutaneous coronary intervention.
aAdjusted for age, sex, body mass index, smoking history (current, former, or never), chronic heart failure on presentation, diabetes, hypertension, hypercholesterolaemia, primary symptom, recent MI, prior PCI, prior coronary artery bypass grafting, history of myocardial infarction, heart failure, cerebral vascular disease, peripheral artery disease, chronic obstructive pulmonary disease, renal dysfunction, presence of tumour/lymphoma/leukaemia, metastatic cancer, ejection fraction ≤40%, ejection fraction unknown, level of stenosis in each coronary vessel (right coronary artery, left anterior descending, left circumflex, left main coronary artery).