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. 2009 May 26;27(21):3465–3471. doi: 10.1200/JCO.2008.20.1301

Table 2.

Patient Characteristics: Univariate Analysis of Predictive Factors for Resection

Categorical Variable Total
Resected
Unresected
P
No. % No. % No. %
Resection status 23 26
Sex
    Male 33 67 10 30 23 70 .002
    Female 16 33 13 81 3 19
Previous chemotherapy
    Pretreated 26 53 10 38 16 62 .26
    Chemotherapy-naïve 23 47 13 57 10 43
Site of disease
    Colon 42 86 21 50 21 50 .42
    Rectum 7 14 2 29 5 71
Dukes' stage
    B 10 20 4 40 6 60 .73
    C 39 80 19 49 20 51
Time to liver metastases
    Synchronous 36 73 18 50 18 50 .53
    Metachronous 13 27 5 38 8 62
Clinical risk score
    ≥ 3 44 90 20 45 24 55 .75
    0-2 5 10 3 60 2 40
Lesions
    > 5 36 73 18 50 18 50 .64
    1-5 13 27 5 38 8 62
    Size > 5 cm 20 41 10 50 10 50 .78
    Size ≤ 5 cm 29 59 13 45 16 55
Lobular involvement
    Bilobar 48 98 23 48 25 52 1
    Unilobar 1 2 0 0 1 100
Bordering vena cava
    Yes 25 51 14 56 11 44 .26
    No 24 49 9 38 15 63
Liver involvement
    ≥ 50 17 35 7 41 10 59 .76
    < 50 32 65 16 50 16 50
    All segments involved 12 24 5 42 7 58 .75
    All hepatic veins involved 12 24 4 33 8 67 .33
    Both portal veins involved 16 33 5 31 11 69 .14
Age, years
    Median 59 53.5 61.5 .22
    Range 25-77 25-71 32-77
CEA, ng/ml
    Median 109.5 75.5 229.3 .08
    Range 3.2-5,340.4 3.2-1,308 5.7-5,340.4
LDH, Units/L
    Median 247 263 215 .57
    Range 94-1,021 94-1020 126-1,021

Abbreviations: CEA, carcinoembryonic antigen; LDH, lactate dehydrogenase.