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. Author manuscript; available in PMC: 2013 May 7.
Published in final edited form as: Int J Imaging Syst Technol. 2012 Feb 14;22(1):23–32. doi: 10.1002/ima.21296

Figure 7.

Figure 7

Monte-Carlo simulation results for extravascular space. (a) Relative signal change as a function of flip angle for three different vessel sizes. (b) Off-resonance dependence of relative signal change. The signal change increases as the off-resonance increases. In a large flip angle, the contrast sensitivity to the off-resonance becomes smaller. (c) Main field strength dependence. As field strength increases, the signal change increases; however, the signal change peak does not shift significantly. (d) Relative signal change as a function of TE. The U-shaped curve resulted from the combination of T2* BOLD effect and the refocusing effect of bSSFP. The significant signal change at TE = 0 suggests the contribution of the multiple echo pathways in the bSSFP fMRI contrast.