Fig. 3.

Histological scores of pancreatic necrosis and lung injury. Pancreas and lung were removed 24 h after induction of severe acute pancreatitis (SAP), and haematoxylin and eosin (H&E) staining was performed. (a) The extent of pancreatic acinar cell necrosis was quantitated morphometrically by an observer who was not aware of the sample identity. (b) Changes in lung histology score. The identified histological changes included congestion, oedema, inflammatory cells and haemorrhaging 24 h after induction of SAP. Histological scores were improved significantly in rats treated with EP compared with pancreatitic rats. *P < 0·05 versus control group and †P < 0·05 versus SAP group, as tested by one-way analysis of variance (anova). Cont: control.