Fig. 8.

Changes in high mobility group box 1 (HMGB1) protein expression in lung tissue after induction of severe acute pancreatitis (SAP) in rats. (a) The expression of HMGB1 in the lung was detected by Western blot at the designated time-points after SAP. Results show the HMGB1/β-actin ratio from Western blots performed at each time-point. Blot shown is representative of three experiments with similar results. (b) Effect of treatment with EP on pulmonary expression of HMGB1 at 24 h after SAP. Pulmonary expressions of HMGB1 and β-actin determined by Western blot analysis in the control group, SAP group and ethyl pyruvate (EP)-treated group. The data shown are representative of three independent experiments. Values are shown means ± standard error. *P < 0·05 versus control group and †P < 0·05 versus SAP group, as tested by one-way analysis of variance (anova). Cont: control.