Table 1.
Clinical and demographic characteristics
| Disease classification | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Location | Behaviour | ||||||||
| n | Age (years) | Male gender | Disease duration (years) | L1 | L2 | L3 | B1 | B2B3 | |
| CTR NC | 11 | 13 (7, 18) | 73% | – | – | – | – | – | – |
| CTR PMN | 10 | 10·8 (7, 15) | 40% | – | – | – | – | – | – |
| CD NC | 55 | 11 (1, 18) | 64% | 2·6 (0, 16) | 13% | 27% | 60% | 76% | 24% |
| CD PMN | 45 | 16·2 (1, 23) | 64% | 4·3 (0, 14) | 14% | 24% | 62% | 64% | 36% |
| CD Sur. | 16 | 13 (7, 18) | 56% | 4·1 (1, 10) | 25% | 0% | 75% | 0% | 100% |
CTR: healthy control; CD: Crohn disease; NC: subjects in which peripheral blood granulocyte–macrophage colony-stimulating factor (GM-CSF) neutralizing capacity was determined; PMN: subjects in which neutrophil function was measured; CD Sur: CD subjects in which ileal surgical specimens were analysed. Date are shown as the mean (range) or frequency. L1, ileal location, L2, colon-only location, L3, ileocolonic location, B1, inflammatory behaviour, B2B3, stricturing/penetrating behaviour.