Table 1.
Characteristics of: (a) FCD cases and controls and (b) controls with and without asthma, in the Ausimmune Study.
| Controls* | FCD cases* | Controls no asthma‡ | Controls asthma‡ | |||
|---|---|---|---|---|---|---|
| n = 539 | n = 279 | n = 421 | n = 133 | |||
| Characteristics | n (%) | n (%) | P-value† | n (%) | n (%) | P-value† |
| Female/male ratio | 419/120 | 214/65 | 322/99 | 110/23 | ||
| Mean age in years at study interview (s.d.) | 38·69 (9·58) | 37·75 (9·57) | 0·18 | 38·64 (9·44) | 39·19 (9·96) | 0·57 |
| Education (tertiary versus other) | 139 (26·0) | 68 (25·4) | 0·67 | 106 (25·3) | 35 (26·7) | 0·75 |
| Ever smoked (ever versus never) | 283 (53·0) | 171 (62·0) | 0·02 | 215 (51·4) | 78 (60·0) | 0·09 |
| Breastfed (ever versus never) | 371 (74·1) | 186 (72·1) | 0·56 | 287 (73·0) | 88 (73·3) | 0·95 |
| Rural residence at birth (yes versus no) | 84 (17·9) | 44 (18·3) | 0·90 | 69 (18·9) | 16 (13·9) | 0·22 |
| Regular childcare < age 6 years (ever versus never) | 209 (40·6) | 128 (47·8) | 0·06 | 165 (40·8) | 51 (41·1) | 0·96 |
| Number of siblings (3 or more versus less) | 220 (41·9) | 118 (42·6) | 0·85 | 180 (43·9) | 48 (37·2) | 0·18 |
| Any older siblings (yes versus no) | 315 (60·1) | 177 (64·8) | 0·19 | 259 (63·3) | 65 (50·4) | 0·009 |
| Any younger siblings (yes versus no) | 371 (70·8) | 170 (62·3) | 0·01 | 282 (68·9) | 99 (76·7) | 0·09 |
Percentages refer to subjects with available data.
*
Matched FCD cases and controls with complete data.
†
Derived from two-sample t-test for proportions comparing cases and controls without missing variables for the variable.
‡
All interviewed controls with allergy data, including those not matched to a participating case. FCD: a first clinical diagnosis of central nervous system demyelination; s.d.: standard deviation.