TABLE 2.

Free cholesterol and cholesteryl ester values in a subset of LCAT mutation carriers and controls

	Controls (n = 29)	Heterozygous carriers (n = 29)	P	Homozygous carriers (n = 3)	P
Total cholesterol, mmol/l	5.3 ± 1.2	4.5 ± 1.2	0.002	4.1 ± 0.6	0.09
FC	1.56 ± 0.35	1.4 ± 0.4	0.04	2.1 ± 0.3	0.02
CE	3.65 ± 1.04	3.0 ± 0.9	0.01	2.0 ± 0.6	0.01
FC/CE ratio	0.48 ± 0.30	0.5 ± 0.1	0.73	1.1 ± 0.4	0.001
Cholesterol after apoB precipitation	1.3 ± 0.4	0.7 ± 0.3	0.03	0.04 ± 0.01	<0.001
FC	1.78 ± 0.71	0.1 ± 0.1	0.13	0.0 ± 0.0	<0.001
CE	0.7 ± 0.2	0.6 ± 0.2	0.02	0.04 ± 0.01	<0.001
FC/CE ratio	0.24 ± 0.06	0 ± 0.12	0.50	1.1 ± 0.4	<0.001

P is for Student's t-test compared with controls. FC, free cholesterol; CE, cholesteryl ester.