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. Author manuscript; available in PMC: 2013 May 7.
Published in final edited form as: Front Biosci (Schol Ed). 2012 Jan 1;4:375–391. doi: 10.2741/274

Figure 4.

Figure 4

Chemical structures of dithiocarbamates.

DDTC, PDTC, and DSF have all been used previously in the clinical setting for a variety of diseases. These complexes are able to chelate copper, and DSF-Cu complexes are active against human tumor cells. EtDTC and PyDTC are metal chelating compounds from the dithiocarbamate family that have been investigated for their proteasome-inhibitory activity.