Chemical structures of dithiocarbamates.
DDTC, PDTC, and DSF have all been used previously in the clinical setting for a variety of diseases. These complexes are able to chelate copper, and DSF-Cu complexes are active against human tumor cells. EtDTC and PyDTC are metal chelating compounds from the dithiocarbamate family that have been investigated for their proteasome-inhibitory activity.